SP100 抗体 (full length)
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北京 101111
Quick Overview for SP100 抗体 (full length) (ABIN7879067)
抗原
See all SP100 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
克隆位点
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抗原表位
- full length
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原理
- SP100 Antibody (azide and preservative free)
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纯化方法
- Protein A/G affinity
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免疫原
- Recombinant full-length human SP100 protein was used as the immunogen for the SP100 antibody.
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亚型
- IgG2b
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anti-SP100 Nuclear Antigen (SP100) (AA 610-802) antibody
SP100 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-SP100 Nuclear Antigen (SP100) (AA 1-98) antibodySP100 适用: 人 WB, ELISA, RNAi 宿主: 小鼠 Monoclonal 1G6 unconjugated
anti-SP100 Nuclear Antigen (SP100) (AA 1-480) antibodySP100 适用: 人 WB, IHC (p) 宿主: 小鼠 Polyclonal unconjugated
anti-SP100 Nuclear Antigen (SP100) (AA 1-480) antibodySP100 适用: 人 WB, IHC (p) 宿主: 小鼠 Polyclonal unconjugated
anti-SP100 Nuclear Antigen (SP100) (AA 1-480) antibodySP100 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-SP100 Nuclear Antigen (SP100) (AA 116-333) antibodySP100 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-SP100 Nuclear Antigen (SP100) (AA 1-98) antibodySP100 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-SP100 Nuclear Antigen (SP100) (AA 181-480) antibodySP100 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-SP100 Nuclear Antigen (SP100) antibodySP100 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-SP100 Nuclear Antigen (SP100) (AA 261-465) antibodySP100 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal dilution of the SP100 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- 1 mg/mL in 1X PBS, BSA free, sodium azide free
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储存液
- Azide free
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储存条件
- -20 °C
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储存方法
- Aliquot the SP100 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- SP100 (SP100 Nuclear Antigen (SP100))
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别名
- SP100
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背景
- The human SP100 gene encodes an autoantigen that co-localizes with PML and NDP52 in distinct nuclear domains, called nuclear dots (NDs) or ND10 nuclear bodies. Papova-, adeno-, and herpesviruses begin their transcription and DNA-replication at NDs, which play a role in autoimmunity, viral infections and in the etiology of acute promyelocytic leukemia. SP-100 is an interferon inducible protein that has two splice variants. One splice variant contains a highly conserved copy of the DNA-binding high mobility group 1 protein sequence, and thus represents a novel HMG-box protein. This alternatively spliced variant of SP-100 has a unique expression and localization pattern that is distinct from the SP-100 full-length protein. The SP100 protein is covalently modified by the small ubiquitin-related protein SUMO-1. SP-100 contains a functional nuclear localization signal and an ND-targeting region, which overlaps with the SP-100 homodimerization domain.
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UniProt
- P23497
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途径
- Retinoic Acid Receptor Signaling Pathway
抗原
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