Recombinant Smoothelin 抗体 (full length)
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Quick Overview for Recombinant Smoothelin 抗体 (full length) (ABIN7879065)
抗原
See all Smoothelin (SMTN) 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
质量等级
克隆位点
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抗原表位
- full length
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原理
- Recombinant Smoothelin Antibody / SMSMO / SMTN (azide and preservative free)
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纯化方法
- Protein A/G affinity
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免疫原
- Recombinant full-length human protein was used as the immunogen for the recombinant Smoothelin antibody.
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亚型
- IgG, kappa
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anti-Smoothelin (SMTN) antibody
SMTN 适用: 人, Cat, 小鸡, 犬, 猴, Pig WB, IHC, IHC (p), IHC (fro) 宿主: 小鼠 Monoclonal R4A unconjugated
anti-Smoothelin (SMTN) antibodySMTN 适用: 人, Cat, 小鸡, 犬, 猴, Pig WB, IHC, ICC, IHC (p), IHC (fro) 宿主: 小鼠 Monoclonal R4A unconjugated
anti-Smoothelin (SMTN) antibodySMTN 适用: 人, 大鼠, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Smoothelin (SMTN) (AA 742-906) antibodySMTN 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Smoothelin (SMTN) (AA 65-325) antibodySMTN 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Smoothelin (SMTN) (AA 748-911) antibodySMTN 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal dilution of the recombinant Smoothelin antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- 1 mg/mL in 1X PBS, BSA free, sodium azide free
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储存液
- Azide free
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储存条件
- -20 °C
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储存方法
- Aliquot the recombinant Smoothelin antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- Smoothelin (SMTN)
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别名
- Smoothelin
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背景
- Smoothelin is found exclusively in contractile smooth muscle cells. It associates with stress fibers and constitutes part of the cytoskeleton. In the vascular system, smoothelin expression is limited to large veins and arteries capable of pulsatile contraction. As a marker for the highly differentiated contractile smooth muscle cell, smoothelin expression is useful for studying vascular malformation and injury. It is a constituent of the smooth muscle cell cytoskeleton protein exclusively found in differentiated smooth muscle cells (SMC). Cells with SMC-like characteristics, such as myofibroblasts and myoepithelial cells, as well as skeletal and cardiac muscle do not contain smoothelin.To distinguish bladder muscularis mucosae (MM) from muscularis propria (MP) muscle bundles is crucial for accurate staging of bladder carcinoma. Strong smoothelin expression is nearly exclusively observed in muscularis propria. Therefore, the staining pattern of MP (strongly positive) and MM (negative or weakly positive) makes this antibody an attractive diagnostic tool. Anti-smoothelin immunostaining can be helpful in differentiating benign (+) from malignant smooth muscle tumors (-), and other mimics (-).
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UniProt
- P53814
抗原
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