SCXA 抗体 (full length)
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北京 101111
Quick Overview for SCXA 抗体 (full length) (ABIN7878979)
抗原
See all SCXA 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- full length
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原理
- Scleraxis Antibody / SCXA
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纯化方法
- Protein A/G affinity
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免疫原
- Recombinant full-length human SCXA protein was used as the immunogen for the Scleraxis antibody.
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亚型
- IgG2a
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应用备注
- Optimal dilution of the Scleraxis antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.2 mg/mL
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缓冲液
- 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot the Scleraxis antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- SCXA (Scleraxis (SCXA))
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别名
- Scleraxis
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背景
- Transcription factors are proteins that bind DNA adjacent to genes and control the production of mRNA transcripts. Scleraxis (basic helix-loop-helix transcription factor scleraxis) is a 201 amino acid protein that dimerizes with another bHLH protein to initiate transcription. Scleraxis is known to play a role in formation of mesoderm and somite-derived chondrogenic lineages. Scleraxis localizes to the nucleus and contains one bHLH domain. bHLH transcription factors, in general, function in cellular differentiation, proliferation, and oncogene regulation. The gene encoding Scleraxis maps to human chromosome 8, which consists of nearly 146 million base pairs, houses more than 800 genes and is associated with a variety of diseases and malignancies. Schizophrenia, bipolar disorder, Trisomy 8, Pfeiffer syndrome, congenital hypothyroidism, Waardenburg syndrome and some leukemias and lymphomas are thought to occur as a result of defects in specific genes that map to chromosome 8.
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UniProt
- Q7RTU7
抗原
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