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SATB1 抗体 (full length)

This 小鼠 单克隆 antibody specifically detects SATB1 in IHC (p). It exhibits reactivity toward 人.
产品编号 ABIN7878974
发货至: 中国
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for SATB1 抗体 (full length) (ABIN7878974)

抗原

See all SATB1 抗体
SATB1 (SATB Homeobox 1 (SATB1))

适用

  • 94
  • 66
  • 47
  • 6
  • 5
  • 3
  • 2
  • 1
  • 1

宿主

  • 78
  • 15
  • 1
小鼠

克隆类型

  • 48
  • 46
单克隆

标记

  • 47
  • 5
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This SATB1 antibody is un-conjugated

应用范围

  • 52
  • 34
  • 32
  • 26
  • 17
  • 14
  • 14
  • 14
  • 13
  • 12
  • 3
  • 2
  • 2
  • 1
  • 1
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

质量等级

Carrier-free

克隆位点

SATB1-2661
  • 抗原表位

    • 16
    • 9
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    full length

    原理

    SATB1 Antibody / Special AT-rich sequence-binding protein 1 (azide and preservative free)

    纯化方法

    Protein A/G affinity

    免疫原

    Recombinant full-length human SATB1 protein was used as the immunogen for the SATB1 antibody.

    亚型

    IgG1
  • 应用备注

    Optimal dilution of the SATB1 antibody should be determined by the researcher.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    1 mg/mL in 1X PBS, BSA free, sodium azide free

    储存液

    Azide free

    储存条件

    -20 °C

    储存方法

    Aliquot the SATB1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
  • 抗原

    SATB1 (SATB Homeobox 1 (SATB1))

    别名

    SATB1

    背景

    The homeoproteins CCAAT displacement protein (CDP) and special AT-rich sequence binding protein 1 (SATB1) are transcriptional repressors of many cellular genes, and they participate in cell development and cell type differentiation. SATB1 is expressed primarily in thymocytes, and, like CDP, it also contains a distinct homeobox DNA-binding domain that is essential for DNA binding. SATB1 and CDP interact through these homeodomains and synergistically function as mediators of gene expression. SATB1 contains an additional domain that has a higher affinity for DNA and specifically facilitates the direct association between SATB1 and the nuclear matrix attachment regions (MARs) of DNA. MARs are specific DNA sequences that bind to the nuclear matrix and form the base of chromosomal loops that organize the chromosomes and regulate DNA transcription and replication within the nucleus. The association of SATB1 with the core unwinding element within the base-unpairing region of MARs requires both the MAR and homeobox binding domains of SATB1.

    UniProt

    Q01826

    途径

    Caspase Cascade in Apoptosis, Activated T Cell Proliferation
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