SATB1 抗体 (pSer47)
(1 reference)-
- 抗原 See all SATB1 抗体
- SATB1 (SATB Homeobox 1 (SATB1))
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抗原表位
- pSer47
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适用
- 人, 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This SATB1 antibody is un-conjugated
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应用范围
- ELISA, Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
- 交叉反应
- 人, 小鼠
- 预测反应
- Dog,Cow,Pig,Chicken,Rabbit
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic phosphopeptide derived from human SATB1 around the phosphorylation site of Ser47
- 亚型
- IgG
- Top Product
- Discover our top product SATB1 Primary Antibody
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anti-SATB Homeobox 1 (SATB1) (AA 484-763) antibody
SATB1 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-SATB Homeobox 1 (SATB1) (C-Term) antibodySATB1 适用: 人, 小鼠, 大鼠, 兔, 豚鼠, 马 WB 宿主: 兔 Polyclonal unconjugated
anti-SATB Homeobox 1 (SATB1) (AA 671-764) antibodySATB1 适用: 人, 小鼠 WB, ELISA, FACS, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-SATB Homeobox 1 (SATB1) (AA 1-763) antibodySATB1 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-SATB Homeobox 1 (SATB1) (Internal Region) antibodyVerified SATB1 适用: 人 WB, IHC, ELISA, IF, FACS 宿主: 山羊 Polyclonal unconjugated
anti-SATB Homeobox 1 (SATB1) antibodySATB1 适用: 人, 小鼠, 大鼠 WB, IHC, IF, IC 宿主: 兔 Polyclonal unconjugated
anti-SATB Homeobox 1 (SATB1) (AA 484-763) antibodySATB1 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-SATB Homeobox 1 (SATB1) (N-Term) antibodySATB1 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-SATB Homeobox 1 (SATB1) (C-Term) antibodySATB1 适用: 人, 小鼠, 兔, 豚鼠, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-SATB Homeobox 1 (SATB1) (C-Term) antibodySATB1 适用: 人, 小鼠, 大鼠, 兔, Pig, 犬 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- 有效期
- 12 months
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: "Phosphorylated SATB1 is associated with the progression and prognosis of glioma." in: Cell death & disease, Vol. 4, pp. e901, (2013) (PubMed).
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: "Phosphorylated SATB1 is associated with the progression and prognosis of glioma." in: Cell death & disease, Vol. 4, pp. e901, (2013) (PubMed).
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- 抗原
- SATB1 (SATB Homeobox 1 (SATB1))
- 别名
- SATB1 (SATB1 产品)
- 别名
- 2610306G12Rik antibody, AW413156 antibody, SATB1 antibody, sb:cb955 antibody, si:ch211-195k18.2 antibody, SATB homeobox 1 antibody, special AT-rich sequence binding protein 1 antibody, SATB homeobox 1a antibody, SATB1 antibody, Satb1 antibody, satb1 antibody, satb1a antibody
- 背景
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Synonyms: DNA-binding protein SATB1, Special AT-rich sequence-binding protein 1, SATB1
Background: Crucial silencing factor contributing to the initiation of X inactivation mediated by Xist RNA that occurs during embryogenesis and in lymphoma (By similarity). Binds to DNA at special AT-rich sequences, the consensus SATB1-binding sequence (CSBS), at nuclear matrix- or scaffold-associated regions. Thought to recognize the sugar-phosphate structure of double-stranded DNA. Transcriptional repressor controlling nuclear and viral gene expression in a phosphorylated and acetylated status-dependent manner, by binding to matrix attachment regions (MARs) of DNA and inducing a local chromatin-loop remodeling. Acts as a docking site for several chromatin remodeling enzymes (e.g. PML at the MHC-I locus) and also by recruiting corepressors (HDACs) or coactivators (HATs) directly to promoters and enhancers. Modulates genes that are essential in the maturation of the immune T-cell CD8SP from thymocytes. Required for the switching of fetal globin species, and beta- and gamma-globin genes regulation during erythroid differentiation. Plays a role in chromatin organization and nuclear architecture during apoptosis. Interacts with the unique region (UR) of cytomegalovirus (CMV). Alu-like motifs and SATB1-binding sites provide a unique chromatin context which seems preferentially targeted by the HIV-1 integration machinery. Moreover, HIV-1 Tat may overcome SATB1-mediated repression of IL2 and IL2RA (interleukin) in T-cells by binding to the same domain than HDAC1. Delineates specific epigenetic modifications at target gene loci, directly up-regulating metastasis-associated genes while down-regulating tumor-suppressor genes. Reprograms chromatin organization and the transcription profiles of breast tumors to promote growth and metastasis.
- 基因ID
- 6304
- UniProt
- Q01826
- 途径
- Caspase Cascade in Apoptosis, Activated T Cell Proliferation
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