RBM8A 抗体 (full length)
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北京 101111
Quick Overview for RBM8A 抗体 (full length) (ABIN7878928)
抗原
See all RBM8A 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
克隆位点
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抗原表位
- full length
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原理
- RBM8A/Y14 Antibody (azide and preservative free)
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纯化方法
- Protein A/G affinity
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免疫原
- Recombinant full-length human RBM8A protein was used as the immunogen for the RBM8A/Y14 antibody.
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亚型
- IgG1
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应用备注
- Optimal dilution of the RBM8A/Y14 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- 1 mg/mL in 1X PBS, BSA free, sodium azide free
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储存液
- Azide free
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储存条件
- -20 °C
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储存方法
- Aliquot the RBM8A/Y14 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- RBM8A (RNA Binding Motif Protein 8A (RBM8A))
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别名
- RBM8A/Y14
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背景
- The exon junction complex (EJC) is a multiprotein complex that assembles approximately 20-24 nucleotides upstream of exon-exon junctions in pre-mRNAs. It is involved in mRNA export, cytoplasmic localization, and nonsense-mediated mRNA decay. Members of the EJC include Y14, Aly/REF, Magoh, RNPS1, SRm160, and DEK. Aly/REF, Magoh, and Y14, identified as RBM8 in mouse and rat, make up the core of the EJC, and these proteins remain stably bound to spliced mRNAs in the cytoplasm until they are translated. Therefore, Y14, Aly/REF, and Magoh have the ability to communicate to the cytoplasm the processing history of the mRNA, including the position of the removed introns. The gene encoding human Y14 encodes three transcripts. Y14 is a ubiquitously expressed protein. Although Y14 shuttles to the cytoplasm, it is predominantly detected in the nucleus and is co-localized with oskar mRNA at the posterior pole of the cell.
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UniProt
- Q9Y5S9
抗原
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