RPA2 抗体 (full length)
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Quick Overview for RPA2 抗体 (full length) (ABIN7878906)
抗原
See all RPA2 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
克隆位点
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抗原表位
- full length
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原理
- RPA32 Antibody / RPA2 / Replication Protein A2 (azide and preservative free)
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纯化方法
- Protein A/G affinity
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免疫原
- Recombinant human full-length Replication Protein A2 protein was used as the immunogen for the RPA32 antibody.
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亚型
- IgG1, kappa
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应用备注
- Optimal dilution of the RPA32 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- 1 mg/mL in 1X PBS, BSA free, sodium azide free
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储存液
- Azide free
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储存条件
- -20 °C
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储存方法
- Aliquot the RPA32 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- RPA2 (Replication Protein A2, 32kDa (RPA2))
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别名
- RPA32
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背景
- Recognizes a protein of 34 kDa, identified as a subunit of Replication Protein A (RPA) (also known as human single-stranded DNA binding protein, or HSSB). RPA from human cells is a stable heterotrimer of 70 kDa, 32-34 kDa, and 11-14 kDa subunits (RPA70, RPA32, and RPA14 respectively). It is involved in DNA replication, repair, and recombination. RPA is required for the SV40 large tumor antigen-catalyzed unwinding of SV40 DNA and stimulates DNA polymerase (pol) alpha and delta. RPA34 is phosphorylated at the G1/S boundary of the cell cycle or upon exposure of cells to DNA damage-inducing agents including ionizing and UV radiation.
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UniProt
- P15927
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途径
- Telomere Maintenance, DNA Damage Repair, Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA
抗原
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