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PLAP 抗体 (full length)

This 小鼠 单克隆 antibody specifically detects PLAP in IHC (p). It exhibits reactivity toward 人.
产品编号 ABIN7878815
发货至: 中国
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Quick Overview for PLAP 抗体 (full length) (ABIN7878815)

抗原

See all PLAP (ALPP) 抗体
PLAP (ALPP) (Placental Alkaline Phosphatase (ALPP))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This PLAP antibody is un-conjugated

应用范围

  • 132
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Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

SPM593
  • 抗原表位

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    full length

    原理

    PLAP Antibody / Placental Alkaline Phosphatase

    纯化方法

    Protein G affinity chromatography

    免疫原

    Recombinant full-length human ALPP/placental alkaline phosphatase protein was used as the immunogen for the PLAP antibody.

    亚型

    IgG2b, kappa
  • 应用备注

    Optimal dilution of the PLAP antibody should be determined by the researcher.

    1. No special pretreatment is required for the immunohistochemical staining of formalin-fixed tissues.
    2. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Prediluted in 1X PBS, 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide, *For IHC use only*

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store the PLAP antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
  • 抗原

    PLAP (ALPP) (Placental Alkaline Phosphatase (ALPP))

    别名

    PLAP

    背景

    Reacts with a 70 kDa membrane-bound isozyme (Regan and Nagao type) of placental Alkaline Phosphatase (PLAP) occurring in the placenta during the 3rd trimester of gestation. It is highly specific for PLAP and shows no cross-reaction with other isozymes of alkaline phosphatase. Anti-PLAP reacts with germ cell tumors and can discriminate between these and other neoplasms. Somatic neoplasms e.g. breast, gastrointestinal, prostatic, and urinary cancers may also immunoreact with antibodies to PLAP. Anti-PLAP positivity in conjunction with anti-keratin negativity favors seminoma over carcinoma. Germ cell tumors are usually anti-keratin positive, but they regularly fail to stain with anti-EMA, whereas most carcinomas stain with anti-EMA. Anti-PLAP has been useful in the diagnosis of gestational trophoblastic disease.

    UniProt

    P05187
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