PLAP 抗体 (full length)
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北京 101111
Quick Overview for PLAP 抗体 (full length) (ABIN7878807)
抗原
See all PLAP (ALPP) 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
克隆位点
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抗原表位
- full length
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原理
- ALPP Antibody / Placental Alkaline Phosphatase (azide and preservative free)
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纯化方法
- Protein A/G affinity
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免疫原
- Recombinant full-length human ALPP protein was used as the immunogen for the ALPP antibody.
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亚型
- IgG2b, kappa
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应用备注
- Optimal dilution of the ALPP antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- 1 mg/mL in 1X PBS, BSA free, sodium azide free
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储存液
- Azide free
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储存条件
- -20 °C
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储存方法
- Aliquot the ALPP antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- PLAP (ALPP) (Placental Alkaline Phosphatase (ALPP))
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别名
- ALPP
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背景
- Reacts with a 70 kDa membrane-bound isozyme (Regan and Nagao type) of Placental Alkaline Phosphatase (PLAP) occurring in the placenta during the 3rd trimester of gestation. It is highly specific for PLAP and shows no cross-reaction with other isozymes of alkaline phosphatase. Anti-PLAP reacts with germ cell tumors and can discriminate between these and other neoplasms. Somatic neoplasms e.g. breast, gastrointestinal, prostatic, and urinary cancers may also immunoreact with antibodies to PLAP. Anti-PLAP positivity in conjunction with anti-keratin negativity favors seminoma over carcinoma. Germ cell tumors are usually anti-keratin positive, but they regularly fail to stain with anti-EMA, whereas most carcinomas stain with anti-EMA. Anti-PLAP has been useful in the diagnosis of gestational trophoblastic disease.
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UniProt
- P05187
抗原
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