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PLAP 抗体 (full length)

The 小鼠 单克隆 anti-PLAP antibody is suitable to detect PLAP in samples from 人. It has been validated for IHC (p).
产品编号 ABIN7878807
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for PLAP 抗体 (full length) (ABIN7878807)

抗原

See all PLAP (ALPP) 抗体
PLAP (ALPP) (Placental Alkaline Phosphatase (ALPP))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This PLAP antibody is un-conjugated

应用范围

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Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

质量等级

Carrier-free

克隆位点

ALPP-4109
  • 抗原表位

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    full length

    原理

    ALPP Antibody / Placental Alkaline Phosphatase (azide and preservative free)

    纯化方法

    Protein A/G affinity

    免疫原

    Recombinant full-length human ALPP protein was used as the immunogen for the ALPP antibody.

    亚型

    IgG2b, kappa
  • 应用备注

    Optimal dilution of the ALPP antibody should be determined by the researcher.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    1 mg/mL in 1X PBS, BSA free, sodium azide free

    储存液

    Azide free

    储存条件

    -20 °C

    储存方法

    Aliquot the ALPP antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
  • 抗原

    PLAP (ALPP) (Placental Alkaline Phosphatase (ALPP))

    别名

    ALPP

    背景

    Reacts with a 70 kDa membrane-bound isozyme (Regan and Nagao type) of Placental Alkaline Phosphatase (PLAP) occurring in the placenta during the 3rd trimester of gestation. It is highly specific for PLAP and shows no cross-reaction with other isozymes of alkaline phosphatase. Anti-PLAP reacts with germ cell tumors and can discriminate between these and other neoplasms. Somatic neoplasms e.g. breast, gastrointestinal, prostatic, and urinary cancers may also immunoreact with antibodies to PLAP. Anti-PLAP positivity in conjunction with anti-keratin negativity favors seminoma over carcinoma. Germ cell tumors are usually anti-keratin positive, but they regularly fail to stain with anti-EMA, whereas most carcinomas stain with anti-EMA. Anti-PLAP has been useful in the diagnosis of gestational trophoblastic disease.

    UniProt

    P05187
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