MEF2D 抗体 (full length)
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北京 101111
Quick Overview for MEF2D 抗体 (full length) (ABIN7878688)
抗原
See all MEF2D 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- full length
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原理
- MEF2D Antibody
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纯化方法
- Protein A/G affinity
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免疫原
- Recombinant full-length human MEF2D protein was used as the immunogen for the MEF2D antibody.
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亚型
- IgG2b
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应用备注
- Optimal dilution of the MEF2D antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.2 mg/mL
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缓冲液
- 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot the MEF2D antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- MEF2D (Myocyte Enhancer Factor 2D (MEF2D))
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别名
- MEF2D
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背景
- The myocyte enhancer factor-2 (MEF-2) family of transcription factors associate with co-repessors or co-activators to regulate development and function of T cells, neuronal cells and muscle cells. Four family members arise from alternatively spliced transcripts, termed MEF-2A, -2B, -2C and -2D. These members bind as homo- and heterodimers to the MEF-2 site in the promoter region of affected genes. Differential regulation in the expression of the four transcripts implies functional distinction for each duing embryogenesis and development. The process of differentiation from mesodermal precursor cells to myoblasts has led to the discovery of a variety of tissue-specific factors that regulate muscle gene expression. The myogenic basic helix-loop-helix proteins, including MyoD, myogenin, Myf-5 and MRF4, are one class of identified factors. A second family of DNA-binding regulatory proteins is the myocyte-specific enhancer factor-2 (MEF-2) family. Each of these proteins binds to the MEF-2 target DNA sequence present in the regulatory regions of many muscle-specific genes.
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UniProt
- Q14814
抗原
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