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LIM Domain Binding 2 Protein 抗体 (full length)

This 小鼠 单克隆 antibody specifically detects LIM Domain Binding 2 Protein in IF, IHC (p) 和 FACS. It exhibits reactivity toward 人.
产品编号 ABIN7878536
发货至: 中国
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Quick Overview for LIM Domain Binding 2 Protein 抗体 (full length) (ABIN7878536)

抗原

See all LIM Domain Binding 2 Protein (LDB2) 抗体
LIM Domain Binding 2 Protein (LDB2) (LIM Domain Binding 2 (LDB2))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This LIM Domain Binding 2 Protein antibody is un-conjugated

应用范围

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Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

质量等级

Carrier-free

克隆位点

PCRP-LDB2-1B10
  • 抗原表位

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    full length

    原理

    LDB2 Antibody / LIM domain binding 2 (azide and preservative free)

    纯化方法

    Protein A/G affinity

    免疫原

    Recombinant full-length human LDB2 protein was used as the immunogen for the LDB2 antibody.

    亚型

    IgG2c, kappa
  • 应用备注

    Optimal dilution of the LDB2 antibody should be determined by the researcher.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    1 mg/mL in 1X PBS, BSA free, sodium azide free

    储存液

    Azide free

    储存条件

    -20 °C

    储存方法

    Aliquot the LDB2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
  • 抗原

    LIM Domain Binding 2 Protein (LDB2) (LIM Domain Binding 2 (LDB2))

    别名

    LDB2

    背景

    The LIM-only (LMO) proteins, LMO1 and LMO2, are nuclear factors that are characterized by a conserved LIM domain. The LIM domain consists of a cysteine-rich zinc-binding motif that is present in a variety of transcription factors, including the LIM homeobox (LHX) proteins expressed in the central nervous system and involved in cell differentiation. LMO1 and LMO2 are expressed in the adult CNS in a cell type-specific manner, where they are differentially regulated by neuronal activity and are involved in regulating the cellular differentiated phenotype of neurons. LMO2 lacks a specific DNA-binding homeobox domain but rather assembles into transcriptional regulatory complexes to mediate gene expression by interacting with the widely expressed nuclear LIM interactor (NLI). NLI, known also as CLIM-1, and the related protein CLIM-2 facilitate the formation of heteromeric LIM complexes and also enhance the nuclear retention of LIM proteins. LMO2 and the related protein LMO4 are expressed in thymic precursor cells. LMO4 is also expressed in mature T cells, cranial neural crest cells, somite, dorsal limb bud mesenchyme, motor neurons, and Schwann cell progenitors.

    UniProt

    O43679

    途径

    Stem Cell Maintenance
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