LIM Domain Binding 2 Protein 抗体 (full length)
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Quick Overview for LIM Domain Binding 2 Protein 抗体 (full length) (ABIN7878536)
抗原
See all LIM Domain Binding 2 Protein (LDB2) 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
克隆位点
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抗原表位
- full length
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原理
- LDB2 Antibody / LIM domain binding 2 (azide and preservative free)
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纯化方法
- Protein A/G affinity
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免疫原
- Recombinant full-length human LDB2 protein was used as the immunogen for the LDB2 antibody.
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亚型
- IgG2c, kappa
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应用备注
- Optimal dilution of the LDB2 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- 1 mg/mL in 1X PBS, BSA free, sodium azide free
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储存液
- Azide free
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储存条件
- -20 °C
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储存方法
- Aliquot the LDB2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- LIM Domain Binding 2 Protein (LDB2) (LIM Domain Binding 2 (LDB2))
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别名
- LDB2
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背景
- The LIM-only (LMO) proteins, LMO1 and LMO2, are nuclear factors that are characterized by a conserved LIM domain. The LIM domain consists of a cysteine-rich zinc-binding motif that is present in a variety of transcription factors, including the LIM homeobox (LHX) proteins expressed in the central nervous system and involved in cell differentiation. LMO1 and LMO2 are expressed in the adult CNS in a cell type-specific manner, where they are differentially regulated by neuronal activity and are involved in regulating the cellular differentiated phenotype of neurons. LMO2 lacks a specific DNA-binding homeobox domain but rather assembles into transcriptional regulatory complexes to mediate gene expression by interacting with the widely expressed nuclear LIM interactor (NLI). NLI, known also as CLIM-1, and the related protein CLIM-2 facilitate the formation of heteromeric LIM complexes and also enhance the nuclear retention of LIM proteins. LMO2 and the related protein LMO4 are expressed in thymic precursor cells. LMO4 is also expressed in mature T cells, cranial neural crest cells, somite, dorsal limb bud mesenchyme, motor neurons, and Schwann cell progenitors.
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UniProt
- O43679
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途径
- Stem Cell Maintenance
抗原
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