LIM Domain Binding 2 Protein 抗体
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Quick Overview for LIM Domain Binding 2 Protein 抗体 (ABIN7861635)
抗原
See all LIM Domain Binding 2 Protein (LDB2) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- LDB2 Antibody
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特异性
- The LIM-only (LMO) proteins, LMO1 and LMO2, are nuclear factors that are characterized by a conserved LIM domain. The LIM domain consists of a cysteine-rich zinc-binding motif that is present in a variety of transcription factors, including the LIM homeobox (LHX) proteins expressed in the central nervous system and involved in cell differentiation. LMO1 and LMO2 are expressed in the adult CNS in a cell type-specific manner, where they are differentially regulated by neuronal activity and are involved in regulating the cellular differentiated phenotype of neurons. LMO2 lacks a specific DNA-binding homeobox domain but rather assembles into transcriptional regulatory complexes to mediate gene expression by interacting with the widely expressed nuclear LIM interactor (NLI). NLI, known also as CLIM-1, and the related protein CLIM-2 facilitate the formation of heteromeric LIM complexes and also enhance the nuclear retention of LIM proteins. LMO2 and the related protein LMO4 are expressed in thymic precursor cells. LMO4 is also expressed in mature T cells, cranial neural crest cells, somite, dorsal limb bud mesenchyme, motor neurons, and Schwann cell progenitors.
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纯化方法
- 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.
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免疫原
- Recombinant full-length human LDB2 protein
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亚型
- IgG2c, kappa
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anti-LIM Domain Binding 2 (LDB2) (AA 1-373) antibody
LDB2 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 1A3 unconjugated
anti-LIM Domain Binding 2 (LDB2) (C-Term) antibodyLDB2 适用: 人, 大鼠, 犬, 马, 兔, Cow, 豚鼠, 猴, Bat WB 宿主: 兔 Polyclonal unconjugated
anti-LIM Domain Binding 2 (LDB2) (N-Term) antibodyLDB2 适用: 人, 小鼠, 大鼠, 马, 兔, Cow, 豚鼠, 小鸡, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-LIM Domain Binding 2 (LDB2) (C-Term) antibodyLDB2 适用: 人, 小鼠, 大鼠, 犬, 马, 兔, Cow, 豚鼠, 斑马鱼, 猴, 非洲爪蟾 WB 宿主: 兔 Polyclonal unconjugated
anti-LIM Domain Binding 2 (LDB2) (AA 61-110) antibodyLDB2 适用: 人, 小鼠, 大鼠, 犬, 马, 兔, 豚鼠, 斑马鱼, 小鸡, 猴, 非洲爪蟾, Bat WB 宿主: 兔 Polyclonal unconjugated
anti-LIM Domain Binding 2 (LDB2) (AA 314-342), (C-Term) antibodyLDB2 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Prepared in 10 mM PBS
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储存液
- Azide free
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储存条件
- -20 °C,-80 °C
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储存方法
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.
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- LIM Domain Binding 2 Protein (LDB2) (LIM Domain Binding 2 (LDB2))
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别名
- LDB2
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背景
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CLIM1, LDB1, LIM domain binding 2
HeLa cells.
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分子量
- 42.7kDa
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基因ID
- 9079, 714330
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UniProt
- O43679
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途径
- Stem Cell Maintenance
抗原
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