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Keratin 10 抗体 (full length)

This 小鼠 单克隆 antibody specifically detects Keratin 10 in IHC (p). It exhibits reactivity toward 人.
产品编号 ABIN7878476
发货至: 中国
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北京 101111
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Room 801-803
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Quick Overview for Keratin 10 抗体 (full length) (ABIN7878476)

抗原

See all Keratin 10 (KRT10) 抗体
Keratin 10 (KRT10)

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This Keratin 10 antibody is un-conjugated

应用范围

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Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

质量等级

Carrier-free

克隆位点

KRT10-6961
  • 抗原表位

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    full length

    原理

    CK10 Antibody / Cytokeratin 10 / KRT10 (azide and preservative free)

    纯化方法

    Protein A/G affinity

    免疫原

    Recombinant full-length human protein was used as the immunogen for the CK10 antibody.

    亚型

    IgG1, kappa
  • 应用备注

    Optimal dilution of the CK10 antibody should be determined by the researcher.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    1 mg/mL in 1X PBS, BSA free, sodium azide free

    储存液

    Azide free

    储存条件

    -20 °C

    储存方法

    Aliquot the CK10 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
  • 抗原

    Keratin 10 (KRT10)

    别名

    CK10

    背景

    This mAb recognizes a protein of 56.5 kDa, identified as cytokeratin 10 (CK10). CK10 is expressed in all suprabasal layers of the epidermis. In the epidermis, expression of CK10 strictly parallels the extent of differentiation, it is absent in the basal layer, appears in the first suprabasal layers and increases in concentration towards the granular layer. However, CK10 is rarely detected in early stages of vulvar squamous carcinomas (tumors less than 2 cm, clinical stage I) regardless of the tumor grade. In larger and more advanced tumors (greater than 2 cm, clinical stages II and III), CK10 is detected very frequently. Expression of CK10 is related to maturation of malignant keratinocytes, being preferentially detected in more differentiated parts.

    UniProt

    P13645
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