Keratin 10 抗体 (full length)
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北京 101111
Quick Overview for Keratin 10 抗体 (full length) (ABIN7878475)
抗原
See all Keratin 10 (KRT10) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- full length
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原理
- Keratin 10 Antibody / Cytokeratin 10 / CK10
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纯化方法
- Protein A/G affinity
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免疫原
- Recombinant full-length human KRT10 protein was used as the immunogen for the Keratin 10 antibody.
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亚型
- IgG1, kappa
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应用备注
- Optimal dilution of the Keratin 10 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.2 mg/mL
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缓冲液
- 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot the Keratin 10 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- Keratin 10 (KRT10)
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别名
- Keratin 10
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背景
- This mAb recognizes a protein of 56.5 kDa, identified as cytokeratin 10 (CK10). CK10 is expressed in all suprabasal layers of the epidermis. In the epidermis, expression of CK10 strictly parallels the extent of differentiation, it is absent in the basal layer, appears in the first suprabasal layers and increases in concentration towards the granular layer. However, CK10 is rarely detected in early stages of vulvar squamous carcinomas (tumors less than 2 cm, clinical stage I) regardless of the tumor grade. In larger and more advanced tumors (greater than 2 cm, clinical stages II and III), CK10 is detected very frequently. Expression of CK10 is related to maturation of malignant keratinocytes, being preferentially detected in more differentiated parts.
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UniProt
- P13645
抗原
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