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IL-10 抗体 (full length)

The 小鼠 单克隆 anti-IL-10 antibody is suitable to detect IL-10 in samples from 人. It has been validated for IHC (p).
产品编号 ABIN7878456
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for IL-10 抗体 (full length) (ABIN7878456)

抗原

See all IL-10 (IL10) 抗体
IL-10 (IL10) (Interleukin 10 (IL10))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This IL-10 antibody is un-conjugated

应用范围

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Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

质量等级

Carrier-free

克隆位点

IL10-8711
  • 抗原表位

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    full length

    原理

    Interleukin 10 Antibody / IL-10 (azide and preservative free)

    纯化方法

    Protein A affinity

    免疫原

    Recombinant full-length human Interleukin 10 (IL10) protein was used as the immunogen for the Interleukin 10 antibody.

    亚型

    IgG1, kappa
  • 应用备注

    Optimal dilution of the Interleukin 10 antibody should be determined by the researcher.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    1 mg/mL in 1X PBS, BSA free, sodium azide free

    储存液

    Azide free

    储存条件

    -20 °C

    储存方法

    Aliquot the Interleukin 10 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
  • 抗原

    IL-10 (IL10) (Interleukin 10 (IL10))

    别名

    Interleukin 10

    背景

    Interleukin 10 (IL10) is a cytokine produced primarily by monocytes and to a lesser extent by lymphocytes. This cytokine has pleiotropic effects in immuno-regulation and inflammation. It down-regulates the expression of Th1 cytokines, MHC class II antigens, and costimulatory molecules on macrophages. It also enhances B cell survival, proliferation, and antibody production. This cytokine can block NF-kappa B activity, and is involved in the regulation of the JAK-STAT signaling pathway. Knockout studies in mice suggested the function of this cytokine as an essential immuno-regulator in the intestinal tract. Mutations in this gene are associated with an increased susceptibility to HIV-1 infection and rheumatoid arthritis.

    UniProt

    P22301

    途径

    Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response, Maintenance of Protein Location, Cancer Immune Checkpoints
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