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HDAC6 抗体 (full length)

This 小鼠 单克隆 antibody specifically detects HDAC6 in IF 和 FACS. It exhibits reactivity toward 人.
产品编号 ABIN7878380
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for HDAC6 抗体 (full length) (ABIN7878380)

抗原

See all HDAC6 抗体
HDAC6 (Histone Deacetylase 6 (HDAC6))

适用

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  • 3
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  • 1
  • 1
  • 1

宿主

  • 124
  • 21
  • 1
小鼠

克隆类型

  • 107
  • 39
单克隆

标记

  • 81
  • 9
  • 4
  • 4
  • 4
  • 4
  • 4
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  • 2
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This HDAC6 antibody is un-conjugated

应用范围

  • 114
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Immunofluorescence (IF), Flow Cytometry (FACS)

克隆位点

PCRP-HDAC6-1A4
  • 抗原表位

    • 27
    • 15
    • 11
    • 9
    • 6
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
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    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    full length

    原理

    HDAC6 Antibody

    纯化方法

    Protein A/G affinity

    免疫原

    Recombinant full-length human HDAC6 protein was used as the immunogen for the HDAC6 antibody.

    亚型

    IgG2a
  • 应用备注

    Optimal dilution of the HDAC6 antibody should be determined by the researcher.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.2 mg/mL

    缓冲液

    0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Aliquot the HDAC6 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
  • 抗原

    HDAC6 (Histone Deacetylase 6 (HDAC6))

    别名

    HDAC6

    背景

    In the intact cell, DNA closely associates with histones and other nuclear proteins to form chromatin. The remodeling of chromatin is believed to be a critical component of transcriptional regulation and a major source of this remodeling is brought about by the acetylation of nucleosomal histones. Acetylation of lysine residues in the amino terminal tail domain of histone results in an allosteric change in the nucleosomal conformation and an increased accessibility to transcription factors by DNA. Conversely, the deacetylation of histones is associated with transcriptional silencing. Several mammalian proteins have been identified as nuclear histone acetylases, including GCN5, PCAF (p300/CBPassociated factor), p300/CBP, HAT1, and the TFIID subunit TAF II p250. Mammalian HDAC1 (also designated HD1), HDAC2 (also designated RPD3) and HDAC3-6, have been identified as histone deacetylases.This enzyme deacetylates lysine residues in histones H2A, H2B, H3 and H4.

    UniProt

    Q9UBN7

    途径

    Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling
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