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HDAC6 抗体 (full length)

The 小鼠 单克隆 anti-HDAC6 antibody (Clone PCRP-HDAC6-1A4) (ABIN7878379) specifically detects HDAC6 in IF 和 FACS. The antibody is reactive with 人 samples.
产品编号 ABIN7878379
发货至: 中国
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北京 101111
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Room 801-803
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Quick Overview for HDAC6 抗体 (full length) (ABIN7878379)

抗原

See all HDAC6 抗体
HDAC6 (Histone Deacetylase 6 (HDAC6))

适用

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宿主

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小鼠

克隆类型

  • 107
  • 39
单克隆

标记

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This HDAC6 antibody is un-conjugated

应用范围

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Immunofluorescence (IF), Flow Cytometry (FACS)

质量等级

Carrier-free

克隆位点

PCRP-HDAC6-1A4
  • 抗原表位

    • 27
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    full length

    原理

    HDAC6 Antibody (azide and preservative free)

    纯化方法

    Protein A/G affinity

    免疫原

    Recombinant full-length human HDAC6 protein was used as the immunogen for the HDAC6 antibody.

    亚型

    IgG2a
  • 应用备注

    Optimal dilution of the HDAC6 antibody should be determined by the researcher.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    1 mg/mL in 1X PBS, BSA free, sodium azide free

    储存液

    Azide free

    储存条件

    -20 °C

    储存方法

    Aliquot the HDAC6 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
  • 抗原

    HDAC6 (Histone Deacetylase 6 (HDAC6))

    别名

    HDAC6

    背景

    In the intact cell, DNA closely associates with histones and other nuclear proteins to form chromatin. The remodeling of chromatin is believed to be a critical component of transcriptional regulation and a major source of this remodeling is brought about by the acetylation of nucleosomal histones. Acetylation of lysine residues in the amino terminal tail domain of histone results in an allosteric change in the nucleosomal conformation and an increased accessibility to transcription factors by DNA. Conversely, the deacetylation of histones is associated with transcriptional silencing. Several mammalian proteins have been identified as nuclear histone acetylases, including GCN5, PCAF (p300/CBPassociated factor), p300/CBP, HAT1, and the TFIID subunit TAF II p250. Mammalian HDAC1 (also designated HD1), HDAC2 (also designated RPD3) and HDAC3-6, have been identified as histone deacetylases.This enzyme deacetylates lysine residues in histones H2A, H2B, H3 and H4.

    UniProt

    Q9UBN7

    途径

    Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling
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