GTF2H2C 抗体 (full length)
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北京 101111
Quick Overview for GTF2H2C 抗体 (full length) (ABIN7878282)
抗原
See all GTF2H2C 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
克隆位点
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抗原表位
- full length
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原理
- GTF2H2C Antibody (azide and preservative free)
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纯化方法
- Protein A/G affinity
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免疫原
- Recombinant full-length human GTF2H2C protein was used as the immunogen for the GTF2H2C antibody.
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亚型
- IgG2c
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应用备注
- Optimal dilution of the GTF2H2C antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- 1 mg/mL in 1X PBS, BSA free, sodium azide free
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储存液
- Azide free
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储存条件
- 4 °C,-20 °C
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储存方法
- Aliquot the GTF2H2C antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- GTF2H2C (General Transcription Factor IIH, Polypeptide 2C (GTF2H2C))
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别名
- GTF2H2C
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背景
- Initiation of transcription from protein-coding genes in eukaryotes is a complex process that requires RNA polymerase II, as well as families of basal transcription factors. Binding of the factor TFIID (TBP) to the TATA box is believed to be the first step in the formation of a multiprotein complex containing several additional factors, including TFIIA, TFIIB, TFIIE, TFIIF and TFIIH. TFIIH (or BTF2) is a multisubunit transcription/DNA repair factor that possesses several enzymatic activities. The core of TFIIH is composed of five subunits, designated p89 (XPB or ERCC3), p62, p52, p44 and p34. Additional subunits of the TFIIH complex are p80 (XPD or ERCC2) and the ternary kinase complex composed of Cdk7, cyclin H and MAT1. Both p89 and p80 have ATP-dependent helicase activity. The p62, p52 and p44 subunits have been shown to be involved in nucleotide excision repair.
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UniProt
- Q6P1K8
抗原
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