GTF2H2C 抗体
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北京 101111
Quick Overview for GTF2H2C 抗体 (ABIN7863485)
抗原
See all GTF2H2C 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- GTF2H2C (Transcription Factor) Antibody
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特异性
- Initiation of transcription from protein-coding genes in eukaryotes is a complex process that requires RNA polymerase II, as well as families of basal transcription factors. Binding of the factor TFIID (TBP) to the TATA box is believed to be the first step in the formation of a multiprotein complex containing several additional factors, including TFIIA, TFIIB, TFIIE, TFIIF and TFIIH. TFIIH (or BTF2) is a multisubunit transcription/DNA repair factor that possesses several enzymatic activities. The core of TFIIH is composed of five subunits, designated p89 (XPB or ERCC3), p62, p52, p44 and p34. Additional subunits of the TFIIH complex are p80 (XPD or ERCC2) and the ternary kinase complex composed of Cdk7, cyclin H and MAT1. Both p89 and p80 have ATP-dependent helicase activity. The p62, p52 and p44 subunits have been shown to be involved in nucleotide excision repair.
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纯化方法
- 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.
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免疫原
- Recombinant full-length human GTF2H2C protein
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亚型
- IgG2c
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anti-General Transcription Factor IIH, Polypeptide 2C (GTF2H2C) (AA 1-260) antibody
GTF2H2C 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-General Transcription Factor IIH, Polypeptide 2C (GTF2H2C) (AA 321-351), (C-Term) antibodyGTF2H2C 适用: 人 WB, IF, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
anti-General Transcription Factor IIH, Polypeptide 2C (GTF2H2C) (AA 314-343), (C-Term) antibodyGTF2H2C 适用: 人 WB, IF, IHC (p) 宿主: 兔 Polyclonal RB29520 unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 200 μg/mL
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缓冲液
- Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
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有效期
- 24 months
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- GTF2H2C (General Transcription Factor IIH, Polypeptide 2C (GTF2H2C))
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别名
- GTF2H2C
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背景
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EVR6, PFM14, PR domain zinc finger protein 17 (PRDM17), RP72, Zinc finger protein 408 (GTF2H2C)
HeLa or Raji cells. Human breast or prostate carcinoma.
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分子量
- 44kDa
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基因ID
- 730394, 422901
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UniProt
- Q6P1K8
抗原
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