EIF4E 抗体 (full length)
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Quick Overview for EIF4E 抗体 (full length) (ABIN7878211)
抗原
See all EIF4E 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
克隆位点
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抗原表位
- full length
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原理
- Eukaryotic translation initiation factor 4E Antibody / EIF4E (azide and preservative free)
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纯化方法
- Protein A/G affinity
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免疫原
- Recombinant full-length human EIF4E/Eukaryotic translation initiation factor 4E protein was used as the immunogen for the Eukaryotic translation initiation factor 4E antibody.
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亚型
- IgG2a
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应用备注
- Optimal dilution of the Eukaryotic translation initiation factor 4E antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- 1 mg/mL in 1X PBS, BSA free, sodium azide free
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储存液
- Azide free
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储存条件
- 4 °C,-20 °C
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储存方法
- Aliquot the Eukaryotic translation initiation factor 4E antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- EIF4E (Eukaryotic Translation Initiation Factor 4E (EIF4E))
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别名
- Eukaryotic translation initiation factor 4E
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背景
- The initiation of protein synthesis in eukaryotic cells is regulated by interactions between protein initiation factors and RNA molecules. The eukaryotic initiation complex eIF4F exists in vitro as a trimeric complex of eIF4E, eIF4A and eIF4G. Together, the complex allows ribosome binding to mRNA by inducing the unwinding of mRNA secondary structures. eIF4E binds to the mRNA cap during an early step in the initiation of protein synthesis. eIF4A acts as an ATP-dependent RNA helicase. eIF4G acts as a bridge between eIF4E, eIF4A and the eIF3 complex.
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UniProt
- P06730
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途径
- BCR Signaling
抗原
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