Recombinant EIF4E 抗体 (pSer209)
Our Local Distributor
北京 101111
Quick Overview for Recombinant EIF4E 抗体 (pSer209) (ABIN5557447)
抗原
See all EIF4E 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- pSer209
-
原理
- phospho-eIF4E (Ser209) Recombinant Antibody
-
交叉反应
- 人, 小鼠, 大鼠
-
纯化方法
- Purified by Protein A.
-
免疫原
- KLH conjugated Synthesised phosphopeptide derived from human EIF4E around the phosphorylation site of Ser209: SG(p-S)TT
-
亚型
- IgG
-
-
-
-
应用备注
- WB(1:300-5000), IHC-P(1:200-400), IHC-F(1:100-500), IF(1:50-200), ICC/IF(1:50-100)
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- Lot specific
-
缓冲液
- 0.01M TBS ( pH 7.4), 1 % BSA, 0.02 % Proclin 300, and 50 % Glycerol
-
储存液
- ProClin
-
注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- 4 °C,-20 °C
-
储存方法
- Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.
-
有效期
- 12 months
-
-
- EIF4E (Eukaryotic Translation Initiation Factor 4E (EIF4E))
-
别名
- eIF4E
-
背景
-
Synonyms: CBP, EIF4F, AUTS19, EIF4E1, EIF4EL1, Eukaryotic translation initiation factor 4E, eIF-4E, eIF4E, eIF-4F 25 kDa subunit, mRNA cap-binding protein
Background: Recognizes and binds the 7-methylguanosine-containing mRNA cap during an early step in the initiation of protein synthesis and facilitates ribosome binding by inducing the unwinding of the mRNAs secondary structures. Component of the CYFIP1-EIF4E-FMR1 complex which binds to the mRNA cap and mediates translational repression. In the CYFIP1-EIF4E-FMR1 complex this subunit mediates the binding to the mRNA cap.
-
基因ID
- 1977
-
UniProt
- P06730
-
途径
- BCR Signaling
抗原
-