EIF2A 抗体 (full length)
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北京 101111
Quick Overview for EIF2A 抗体 (full length) (ABIN7878206)
抗原
See all EIF2A 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- full length
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原理
- EIF2A Antibody
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纯化方法
- Protein A/G affinity
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免疫原
- Recombinant full-length human EIF2S1 protein was used as the immunogen for the EIF2A antibody.
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亚型
- IgG1
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anti-Eukaryotic Translation Initiation Factor 2A, 65kDa (EIF2A) (AA 448-576) antibody
EIF2A 适用: 人, 小鼠, 大鼠, 猴 WB, IHC, ELISA, FACS 宿主: 小鼠 Monoclonal 3A7B11 unconjugated
anti-Eukaryotic Translation Initiation Factor 2A, 65kDa (EIF2A) (AA 448-576) antibodyEIF2A 适用: 人 WB, IHC, ELISA, FACS, ICC 宿主: 小鼠 Monoclonal 3A7A8 unconjugated
anti-Eukaryotic Translation Initiation Factor 2A, 65kDa (EIF2A) antibodyEIF2A 适用: 人, 小鼠, 大鼠, 猴, 鱼 WB, IHC, IF, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Eukaryotic Translation Initiation Factor 2A, 65kDa (EIF2A) antibodyEIF2A 适用: 人 WB, IHC 宿主: 兔 Monoclonal unconjugated
anti-Eukaryotic Translation Initiation Factor 2A, 65kDa (EIF2A) antibodyKD Validated EIF2A 适用: 人 WB, FACS 宿主: 兔 Monoclonal 25GB4195 unconjugated Recombinant Antibody
anti-Eukaryotic Translation Initiation Factor 2A, 65kDa (EIF2A) (pSer51) antibodyKD Validated EIF2A 适用: 人 WB, FACS, IF (p) 宿主: 兔 Monoclonal 24GB3905 unconjugated Recombinant Antibody
anti-Eukaryotic Translation Initiation Factor 2A, 65kDa (EIF2A) (AA 437-465) antibodyEIF2A 适用: 人 WB, IHC, ELISA, FACS 宿主: 兔 Polyclonal unconjugated
anti-Eukaryotic Translation Initiation Factor 2A, 65kDa (EIF2A) (AA 1-100) antibodyEIF2A 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3D5 unconjugated
anti-Eukaryotic Translation Initiation Factor 2A, 65kDa (EIF2A) antibodyEIF2A 适用: 人, 小鼠, 大鼠, 猴 WB, IF, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Eukaryotic Translation Initiation Factor 2A, 65kDa (EIF2A) (Center) antibodyEIF2A 适用: 人, 小鼠, 大鼠 WB, IF, ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal dilution of the EIF2A antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.2 mg/mL
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缓冲液
- 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot the EIF2A antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- EIF2A (Eukaryotic Translation Initiation Factor 2A, 65kDa (EIF2A))
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别名
- EIF2A
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背景
- The initiation of protein synthesis in eukaryotic cells is regulated by interactions between protein initiation factors and RNA molecules. The eukaryotic initiation complex is composed of three subunits, designated eIF2a, eIF2b and eIF2g (eukaryotic translation initiation factor 2 a, band g, respectively), all of which work in concert to form a ternary complex with GTP and tRNA in the early stages of protein synthesis. eIF2a, also known as EIF2S1 or EIF2, is a 315 amino acid subunit of the eukaryotic initiation complex that functions to bind tRNA to the 40S ribosomal subunit (in a GTP-dependent manner), thereby initiating translation. In addition, the phosphorylation state of eIF2a controls the rate of tRNA translation. When eIF2a is not phosphorylated, translation occurs at a normal rate. However, upon phosphorylation by one of several kinases, eIF2a is stabilized, thus preventing the GDP/GTP exchange reaction and slowing translation.
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UniProt
- P05198
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途径
- Ribonucleoprotein Complex Subunit Organization, ER-Nucleus Signaling, Hepatitis C, Methionine Biosynthetic Process, Ribosome Assembly
抗原
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