ECD/SGT1 抗体 (full length)
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Quick Overview for ECD/SGT1 抗体 (full length) (ABIN7878151)
抗原
See all ECD/SGT1 (ECD) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- full length
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原理
- ECD Antibody / SGT1
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纯化方法
- Protein A/G affinity
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免疫原
- Recombinant full-length human protein was used as the immunogen for the ECD antibody.
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亚型
- IgG2b
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应用备注
- Optimal dilution of the ECD antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.2 mg/mL
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缓冲液
- 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot the ECD antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- ECD/SGT1 (ECD) (Ecdysoneless Homolog (ECD))
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别名
- ECD
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背景
- Inhibits MDM2-mediated degradation of p53/TP53 possibly by cooperating in part with TXNIP. May be involved transcriptional regulation. In vitro has intrinsic transactivation activity enhanced by EP300. May be a transcriptional activator required for the expression of glycolytic genes. Involved in regulation of cell cycle progression. Proposed to disrupt Rb-E2F binding leading to transcriptional activation of E2F proteins. The cell cycle -regulating function may depend on its RUVBL1-mediated association with the R2TP complex. May play a role in regulation of pre-mRNA splicing.
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UniProt
- O95905
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途径
- Regulation of Carbohydrate Metabolic Process
抗原
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