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ECD/SGT1 抗体 (full length)

The 小鼠 单克隆 anti-ECD/SGT1 antibody (Clone PCRP-ECD-1D10) (ABIN7878151) specifically detects ECD/SGT1 in IF 和 FACS. The antibody is reactive with 人 samples.
产品编号 ABIN7878151
发货至: 中国
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Quick Overview for ECD/SGT1 抗体 (full length) (ABIN7878151)

抗原

See all ECD/SGT1 (ECD) 抗体
ECD/SGT1 (ECD) (Ecdysoneless Homolog (ECD))

适用

  • 32
  • 5
  • 5
  • 5
  • 4
  • 4
  • 4
  • 4
  • 3
  • 3
  • 1

宿主

  • 25
  • 7
小鼠

克隆类型

  • 26
  • 6
单克隆

标记

  • 22
  • 2
  • 1
  • 1
  • 1
  • 1
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  • 1
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  • 1
This ECD/SGT1 antibody is un-conjugated

应用范围

  • 19
  • 12
  • 9
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  • 2
Immunofluorescence (IF), Flow Cytometry (FACS)

克隆位点

PCRP-ECD-1D10
  • 抗原表位

    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
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    • 1
    • 1
    • 1
    • 1
    full length

    原理

    ECD Antibody / SGT1

    纯化方法

    Protein A/G affinity

    免疫原

    Recombinant full-length human protein was used as the immunogen for the ECD antibody.

    亚型

    IgG2b
  • 应用备注

    Optimal dilution of the ECD antibody should be determined by the researcher.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.2 mg/mL

    缓冲液

    0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Aliquot the ECD antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
  • 抗原

    ECD/SGT1 (ECD) (Ecdysoneless Homolog (ECD))

    别名

    ECD

    背景

    Inhibits MDM2-mediated degradation of p53/TP53 possibly by cooperating in part with TXNIP. May be involved transcriptional regulation. In vitro has intrinsic transactivation activity enhanced by EP300. May be a transcriptional activator required for the expression of glycolytic genes. Involved in regulation of cell cycle progression. Proposed to disrupt Rb-E2F binding leading to transcriptional activation of E2F proteins. The cell cycle -regulating function may depend on its RUVBL1-mediated association with the R2TP complex. May play a role in regulation of pre-mRNA splicing.

    UniProt

    O95905

    途径

    Regulation of Carbohydrate Metabolic Process
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