DMRT2 抗体 (full length)
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北京 101111
Quick Overview for DMRT2 抗体 (full length) (ABIN7878145)
抗原
See all DMRT2 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- full length
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原理
- DMRT2 Antibody
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纯化方法
- Protein A/G affinity
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免疫原
- Recombinant full-length human DMRT2 protein was used as the immunogen for the DMRT2 antibody.
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亚型
- IgG2b
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应用备注
- Optimal dilution of the DMRT2 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.2 mg/mL
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缓冲液
- 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot the DMRT2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- DMRT2 (Doublesex and Mab-3 Related Transcription Factor 2 (DMRT2))
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别名
- DMRT2
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背景
- The protein encoded by this gene belongs to the DMRT gene family, sharing a DM DNA-binding domain with Drosophila (dsx) and C. elegans mab3, genes involved in sex determination in these organisms. Also, this gene is located in a region of the human genome (chromosome 9p24.3) associated with gonadal dysgenesis and XY sex reversal. Hence this gene is one of the candidates for sex-determining gene(s) on chr 9. Transcriptional activator that directly regulates early activation of the myogenic determination gene MYF5 by binding in a sequence-specific manner to the early epaxial enhancer element of it. Involved in somitogenesis during embryogenesis and somite development and differentiation into sclerotome and dermomyotome. Required for the initiation and/or maintenance of proper organization of the sclerotome, dermomyotome and myotome (By similarity).
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UniProt
- Q9Y5R5
抗原
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