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DMRT2 抗体

The 小鼠 单克隆 anti-DMRT2 antibody is suitable to detect DMRT2 in samples from 人. It has been validated for WB 和 FACS.
产品编号 ABIN7126200
发货至: 中国
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Quick Overview for DMRT2 抗体 (ABIN7126200)

抗原

See all DMRT2 抗体
DMRT2 (Doublesex and Mab-3 Related Transcription Factor 2 (DMRT2))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This DMRT2 antibody is un-conjugated

应用范围

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Western Blotting (WB), Flow Cytometry (FACS)

克隆位点

PCRP-DMRT2-1B11
  • 原理

    DMRT2 (Transcription Factor) Antibody

    特异性

    The protein encoded by this gene belongs to the DMRT gene family, sharing a DM DNA-binding domain with Drosophila 'doublesex' (dsx) and C. elegans mab3, genes involved in sex determination in these organisms. Also, this gene is located in a region of the human genome (chromosome 9p24.3) associated with gonadal dysgenesis and XY sex reversal. Hence this gene is one of the candidates for sex-determining gene(s) on chr 9. Transcriptional activator that directly regulates early activation of the myogenic determination gene MYF5 by binding in a sequence-specific manner to the early epaxial enhancer element of it. Involved in somitogenesis during embryogenesis and somite development and differentiation into sclerotome and dermomyotome. Required for the initiation and/or maintenance of proper organization of the sclerotome, dermomyotome and myotome (By similarity).

    交叉反应 (详细)

    Human.

    纯化方法

    200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

    免疫原

    Recombinant full-length human DMRT2 protein

    亚型

    IgG2b
  • 应用备注

    Known_Application: Flow Cytometry (1-2 μg/million cells), ,Western Blot (1-2 μg/mL), ,Optimal dilution for a specific application should be determined.

    Positive_Control: HeLa or MCF-7 cells.

    限制

    仅限研究用
  • 浓度

    1.0 mg/mL

    缓冲液

    Prepared in 10  mM PBS

    储存液

    Azide free

    储存条件

    -20 °C,-80 °C

    储存方法

    Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

    有效期

    24 months
  • 抗原

    DMRT2 (Doublesex and Mab-3 Related Transcription Factor 2 (DMRT2))

    别名

    DMRT2

    背景

    doublesex and mab-3 related transcription factor 2, doublesex-like 2 protein (DSXL-2), terra like protein antibody

    HeLa or MCF-7 cells.

    分子量

    62kDa

    基因ID

    10655, 59506

    UniProt

    Q9Y5R5
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