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Desmin 抗体 (full length)

This 小鼠 单克隆 antibody specifically detects Desmin in IHC (p). It exhibits reactivity toward 人, 犬, Cow, 马 和 Cat.
产品编号 ABIN7878131
发货至: 中国
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中国
北京 101111
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Beijing Economic Technological Development Area
Room 801-803
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Quick Overview for Desmin 抗体 (full length) (ABIN7878131)

抗原

See all Desmin (DES) 抗体
Desmin (DES)

适用

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人, 犬, Cow, 马, Cat

宿主

  • 144
  • 75
  • 2
小鼠

克隆类型

  • 114
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  • 1
单克隆

标记

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This Desmin antibody is un-conjugated

应用范围

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Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

DES-3255
  • 抗原表位

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    full length

    原理

    Desmin Antibody

    纯化方法

    Protein A/G affinity

    免疫原

    Recombinant full-length human desmin protein was used as the immunogen for the Desmin antibody.

    亚型

    IgG2b, kappa
  • 应用备注

    Optimal dilution of the Desmin antibody should be determined by the researcher.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.2 mg/mL

    缓冲液

    0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Aliquot the Desmin antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
  • 抗原

    Desmin (DES)

    别名

    Desmin

    背景

    Cytoskeletal intermediate filaments (IFs) constitute a diverse group of proteins that are expressed in a highly tissue-specific manner. IFs are constructed from two-chain -helical coiled-coil molecules arranged on an imperfect helical lattice, and have been widely used as markers for distinguishing individual cell types within a tissue and identifying the origins of metastatic tumors. Vimentin is an IF general marker of cells originating in the mesenchyme. Vimentin and Desmin, a related class III IF, are both expressed during skeletal muscle development. Desmin, a 469 amino acid protein found near the Z line in sarcomeres, is expressed more frequently in adult differentiated state tissues. Anti-desmin detects cells of normal smooth, skeletal, and cardiac muscles.Antibody reacts with leiomyomas, leiomyosarcoma, rhabdomyomas, rhabdomyosarcoma, and perivascular cells of glomus tumors of the skin.

    UniProt

    P17661
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