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DAXX 抗体 (full length)

This 小鼠 单克隆 antibody specifically detects DAXX in IF 和 FACS. It exhibits reactivity toward 人.
产品编号 ABIN7878116
发货至: 中国
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北京 101111
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Room 801-803
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Quick Overview for DAXX 抗体 (full length) (ABIN7878116)

抗原

See all DAXX 抗体
DAXX (Death-Domain Associated Protein (DAXX))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This DAXX antibody is un-conjugated

应用范围

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Immunofluorescence (IF), Flow Cytometry (FACS)

质量等级

Carrier-free

克隆位点

PCRP-DAXX-6A8
  • 抗原表位

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    full length

    原理

    Daxx Antibody (azide and preservative free)

    纯化方法

    Protein A/G affinity

    免疫原

    Recombinant full-length human DAXX protein was used as the immunogen for the Daxx antibody.

    亚型

    IgG2c
  • 应用备注

    Optimal dilution of the Daxx antibody should be determined by the researcher.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    1 mg/mL in 1X PBS, BSA free, sodium azide free

    储存液

    Azide free

    储存条件

    -20 °C

    储存方法

    Aliquot the Daxx antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
  • 抗原

    DAXX (Death-Domain Associated Protein (DAXX))

    别名

    Daxx

    背景

    This gene encodes a multifunctional protein that resides in multiple locations in the nucleus and in the cytoplasm. It interacts with a wide variety of proteins, such as apoptosis antigen Fas, centromere protein C, and transcription factor erythroblastosis virus E26 oncogene homolog 1. In the nucleus, the encoded protein functions as a potent transcription repressor that binds to sumoylated transcription factors. Its repression can be relieved by the sequestration of this protein into promyelocytic leukemia nuclear bodies or nucleoli. This protein also associates with centromeres in G2 phase. In the cytoplasm, the encoded protein may function to regulate apoptosis. The subcellular localization and function of this protein are modulated by post-translational modifications, including sumoylation, phosphorylation and polyubiquitination. Alternative splicing results in multiple transcript variants.

    UniProt

    Q9UER7

    途径

    Intracellular Steroid Hormone Receptor Signaling Pathway
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