Recombinant CD99 抗体 (full length)
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北京 101111
Quick Overview for Recombinant CD99 抗体 (full length) (ABIN7877973)
抗原
See all CD99 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
质量等级
克隆位点
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抗原表位
- full length
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原理
- CD99 Antibody (azide and preservative free)
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纯化方法
- Protein G affinity chromatography
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免疫原
- Recombinant full-length human MIC2/CD99 protein was used as the immunogen for the CD99 antibody.
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亚型
- IgM, kappa
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应用备注
- Optimal dilution of the CD99 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- 1 mg/mL in 1X PBS, BSA free, sodium azide free
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储存液
- Azide free
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储存条件
- 4 °C,-20 °C
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储存方法
- Store the CD99 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
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- CD99
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别名
- CD99
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背景
- Recognizes a sialoglycoprotein of 27-32 kDa, identified as CD99, or MIC2 gene product, or E2 antigen. MIC2 gene is located in the pseudo-autosomal region of the human X and Y chromosome. MIC2 gene encodes two distinct proteins, which are produced by alternative splicing of the CD99 gene transcript and are identified as bands of 30 and 32 kDa (p30/32).Although its function is not fully understood, CD99 is implicated in various cellular processes including homotypic aggregation of T cells, upregulation of T cell receptor and MHS molecules, apoptosis of immature thymocytes and leukocyte diapedesis.CD99 is expressed on the cell membrane of some lymphocytes, cortical thymocytes, and granulosa cells of the ovary. Most pancreatic islet cells, Sertoli cells of the testis, and some endothelial cells express this antigen. Mature granulocytes express very little or no CD99. MIC2 is strongly expressed on Ewing s sarcoma cells and primitive peripheral neuroectodermal tumors.
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UniProt
- P14209
抗原
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