CD34 抗体 (full length)
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北京 101111
Quick Overview for CD34 抗体 (full length) (ABIN7877864)
抗原
See all CD34 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
克隆位点
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抗原表位
- full length
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原理
- CD34 Antibody (azide and preservative free)
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纯化方法
- Protein A/G affinity
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免疫原
- Recombinant full-length human HPCA1 protein was used as the immunogen for the CD34 antibody.
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亚型
- IgG1, kappa
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应用备注
- Optimal dilution of the CD34 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- 1 mg/mL in 1X PBS, BSA free, sodium azide free
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储存液
- Azide free
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储存条件
- -20 °C
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储存方法
- Aliquot the CD34 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- CD34
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别名
- CD34
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背景
- This MAb recognizes a single chain, transmembrane,heavily glycosylated protein of 90-120 kDa, which is identified as CD34. On the basis of differential sensitivity to degradation by specific enzymes, epitopes of monoclonal antibodies to CD34 are classified intothree main categories, class I, class II and class III. It is a class II antibody whose epitope is resistant to neuraminidasebut sensitive to glycoprotease and chymopapain.CD34 expression is a hallmark for identifying pluripotent hematopoietic stem or progenitor cells. Its expression is gradually lost as lineage committed progenitors differentiate. CD34 is a marker of choice for staining blasts in acute myeloid leukemia. In addition, CD34 is expressed by soft tissue tumors, such as solitary fibrous tumor and gastrointestinal stromal tumor. Its expression is also found in vascular endothelium. It appears that proliferating endothelial cells express this molecule more than the non-proliferating endothelial cells. Anti-CD34 labels 85 % of angiosarcoma and Kaposi s sarcoma, but with a lower specificity.
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UniProt
- P28906
抗原
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