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BTLA 抗体 (Extracellular)

This 小鼠 单克隆 antibody specifically detects BTLA in ELISA. It exhibits reactivity toward 人.
产品编号 ABIN7877534
发货至: 中国
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北京 101111
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Room 801-803
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Quick Overview for BTLA 抗体 (Extracellular) (ABIN7877534)

抗原

See all BTLA 抗体
BTLA (B and T Lymphocyte Associated (BTLA))

适用

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宿主

  • 54
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小鼠

克隆类型

  • 77
  • 42
  • 2
单克隆

标记

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This BTLA antibody is un-conjugated

应用范围

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  • 9
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ELISA

质量等级

Carrier-free

克隆位点

BTLA-1528
  • 抗原表位

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    Extracellular

    原理

    BTLA Antibody / CD272 (azide and preservative free)

    纯化方法

    Protein G affinity chromatography

    免疫原

    Recombinant extracellular human CD272/BTLA protein was used as the immunogen for this BTLA antibody.

    亚型

    IgG2b, kappa
  • 应用备注

    Optimal dilution of the BTLA antibody should be determined by the researcher.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    1 mg/mL in 1X PBS, BSA free, sodium azide free

    储存液

    Azide free

    储存条件

    4 °C,-20 °C

    储存方法

    Store the BTLA antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
  • 抗原

    BTLA (B and T Lymphocyte Associated (BTLA))

    别名

    BTLA

    背景

    B and T lymphocyte attenuator (BTLA) is an immunoglobulin domain-containing glycoprotein whose expression is induced during T-cell activation. BTLA is similar to CTLA-4 and PD-1, all of which are coinhibitory receptors belonging to the CD28 family. However, unlike CTLA-4 and PD-1, BTLA does not interact with B7-Ig family counter receptors. Rather, the herpesvirus entry mediator (HVEM), a TNF receptor, acts as a molecular switch that modulates T-cell activation by propagating inhibitory signals through BTLA. The BTLAHVEM interaction is conserved between Mouse and human, suggesting that this system is an important pathway regulating lymphocyte activation.

    UniProt

    Q7Z6A9

    途径

    Cancer Immune Checkpoints
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