GRIN1/NMDAR1 抗体 (pSer890)
Quick Overview for GRIN1/NMDAR1 抗体 (pSer890) (ABIN744278)
抗原
See all GRIN1/NMDAR1 (GRIN1) 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- pSer890
-
特异性
- This phosphorylation site is homologous to that of Ser890 in Mouse and Rat.
-
交叉反应
- 人, 大鼠
-
预测反应
- Mouse,Dog,Cow,Chicken
-
纯化方法
- Purified by Protein A.
-
免疫原
- KLH conjugated synthetic phosphopeptide derived from human NMDAR1 around the phosphorylation site of Ser890
-
亚型
- IgG
-
-
-
-
应用备注
-
WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 μg/μL
-
缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
-
储存液
- ProClin
-
注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
-
储存条件
- 4 °C,-20 °C
-
储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
-
有效期
- 12 months
-
-
- GRIN1/NMDAR1 (GRIN1) (Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 1 (GRIN1))
-
别名
- NMDAR1
-
背景
-
Synonyms: NR1, MRD8, GluN1, NMDA1, NMDAR1, Glutamate receptor ionotropic, NMDA 1, Glutamate [NMDA] receptor subunit zeta-1, N-methyl-D-aspartate receptor subunit NR1, NMD-R1, GRIN1
Background: NMDA receptor subtype of glutamate-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium. Mediated by glycine. This protein plays a key role in synaptic plasticity, synaptogenesis, excitotoxicity, memory acquisition and learning. It mediates neuronal functions in glutamate neurotransmission. Is involved in the cell surface targeting of NMDA receptors (By similarity).
-
基因ID
- 2902
-
UniProt
- Q05586
-
途径
- Synaptic Membrane, Feeding Behaviour, Regulation of long-term Neuronal Synaptic Plasticity
抗原
-