Recombinant UBA3 抗体 (Catalytic Subunit)
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Quick Overview for Recombinant UBA3 抗体 (Catalytic Subunit) (ABIN7877514)
抗原
See all UBA3 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- Catalytic Subunit
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原理
- UBA3 Antibody / Ubiquitin-activating enzyme 3 / UBE1C
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纯化方法
- Affinity chromatography
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免疫原
- A synthetic peptide from human NEDD8-activating enzyme E1 catalytic subunit protein was used as the immunogen for the UBA3 antibody.
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亚型
- IgG
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应用备注
- Optimal dilution of the UBA3 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Antibody in PBS with 0.02 % sodium azide, 50 % glycerol and 0.4-0.5 mg/mL BSA
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store the UBA3 antibody at -20oC.
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- UBA3 (Ubiquitin-Like Modifier Activating Enzyme 3 (UBA3))
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别名
- UBA3
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背景
- NEDD8-activating enzyme E1 catalytic subunit (UBA3) is the catalytic subunit of the dimeric UBA3-NAE1 E1 enzyme. E1 activates NEDD8 by first adenylating its C-terminal glycine residue with ATP, thereafter linking this residue to the side chain of the catalytic cysteine, yielding a NEDD8-UBA3 thioester and free AMP. E1 finally transfers NEDD8 to the catalytic cysteine of UBE2M. Down-regulates steroid receptor activity. Necessary for cell cycle progression. [UniProt]
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UniProt
- Q8TBC4
抗原
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