Recombinant VLDLR 抗体 (C-Term)
Our Local Distributor
北京 101111
Quick Overview for Recombinant VLDLR 抗体 (C-Term) (ABIN7877495)
抗原
See all VLDLR 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
抗原表位
- C-Term
-
原理
- VLDLR Antibody / VLDL Receptor
-
纯化方法
- Protein A/G affinity
-
免疫原
- A recombinant human protein fragment from the C-terminal region was used as the immunogen for the VLDLR antibody.
-
亚型
- IgG1, kappa
-
-
-
-
应用备注
- Optimal dilution of the VLDLR antibody should be determined by the researcher.
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 0.2 mg/mL
-
缓冲液
- 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Aliquot the VLDLR antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
-
-
- VLDLR (Very Low Density Lipoprotein Receptor (VLDLR))
-
别名
- VLDLR
-
背景
- VLDLR (very low density lipoprotein receptor) is a member of the LDL receptor gene family, which includes LDL receptor, LRP, megalin, VLDLR and ApoER2. The LDL receptor family is characterized by a cluster of cysteine-rich class A repeats, epidermal growth factor (EGF)-like repeats, YWTD repeats and an O-linked sugar domain. VLDLR associates with RAP (receptor associated protein) during receptor folding, and RAP facilitates the secretion of the extracellular region of VLDLR. VLDLR is thought to mediate the interaction of extracellular Reelin and cytosolic mDab1 (mammalian disabled protein), which activates a tyrosine kinase. This pathway regulates the migration of neurons along the radial glial fiber network during brain development.
-
UniProt
- P98155
-
途径
- Cellular Response to Molecule of Bacterial Origin
抗原
-