PLAP 抗体 (C-Term)
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Quick Overview for PLAP 抗体 (C-Term) (ABIN7877456)
抗原
See all PLAP (ALPP) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- C-Term
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原理
- Placental Alkaline Phosphatase Antibody / ALPP / PLAP
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序列
- KARDRKAYTV LLYGNGPGYV LKDGARPDVT E
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纯化方法
- Antigen affinity purified
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免疫原
- C-terminal amino acids KARDRKAYTVLLYGNGPGYVLKDGARPDVTE were used as the immunogen for the Placental Alkaline Phosphatase antibody.
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亚型
- IgG2b
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应用备注
- Optimal dilution of the Placental Alkaline Phosphatase antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the Placental Alkaline Phosphatase antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- PLAP (ALPP) (Placental Alkaline Phosphatase (ALPP))
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别名
- Placental Alkaline Phosphatase
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背景
- Alkaline phosphatase, placental type also known as placental alkaline phosphatase (PLAP) is an allosteric enzyme that in humans is encoded by the ALPP gene. The protein encoded by this gene is an alkaline phosphatase, a metalloenzyme that catalyzes the hydrolysis of phosphoric acid monoesters. It belongs to a multigene family composed of four alkaline phosphatase isoenzymes. The enzyme functions as a homodimer and has a catalytic site containing one magnesium and two zinc ions, which are required for its enzymatic function. The protein is primarily expressed in placental and endometrial tissue, however, strong ectopic expression has been detected in ovarian adenocarcinoma, serous cystadenocarcinoma, and other ovarian cancer cells.
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UniProt
- P05187
抗原
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