KRT14 抗体 (C-Term) (Biotin)
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北京 101111
Quick Overview for KRT14 抗体 (C-Term) (Biotin) (ABIN7877409)
抗原
See all KRT14 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- C-Term
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原理
- Cytokeratin 14 Antibody
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纯化方法
- Protein G affinity chromatography
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免疫原
- A synthetic peptide of 15 amino acid from the C-terminus of the human protein was used as the immunogen for the Cytokeratin 14 antibody.
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亚型
- IgG3, kappa
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应用备注
- Optimal dilution of the Cytokeratin 14 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- 0.1 mg/mL with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store the Cytokeratin 14 antibody at 2-8oC (up to one month) or aliquot and store at -20oC (longer term).
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- KRT14 (Keratin 14 (KRT14))
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别名
- Cytokeratin 14
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背景
- Cytokeratin 14 (CK14) belongs to the type I (or A or acidic) subfamily of low molecular weight keratins and exists in combination with keratin 5 (type II or B or basic). CK14 is found in basal cells of squamous epithelia, some glandular epithelia, myoepithelium, and mesothelial cells. Anti-CK14 is useful in differentiating squamous cell carcinomas from poorly differentiated epithelial tumors. Anti-CK14 is one of the specific basal markers for distinguishing between basal and non-basal subtypes of breast carcinomas. Anti-CK14 is also a good marker for differentiation of intraductal from invasive salivary duct carcinoma by the positive staining of basal cells surrounding the in-situ neoplasm as well as for differentiation of benign prostate from prostate carcinoma. Furthermore, this antibody has been useful in separating oncocytic tumors of the kidney from its renal mimics, and in identifying metaplastic carcinomas of the breast.
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UniProt
- P02533
抗原
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