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KRT14 抗体 (C-Term) (Biotin)

The 小鼠 单克隆 anti-KRT14 antibody is suitable to detect KRT14 in samples from 人, 大鼠 和 小鼠. It has been validated for WB, IF, FACS 和 IHC (p).
产品编号 ABIN7877409
发货至: 中国
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中国
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Room 801-803
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for KRT14 抗体 (C-Term) (Biotin) (ABIN7877409)

抗原

See all KRT14 抗体
KRT14 (Keratin 14 (KRT14))

适用

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人, 大鼠, 小鼠

宿主

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小鼠

克隆类型

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单克隆

标记

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This KRT14 antibody is conjugated to Biotin

应用范围

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Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

LL002
  • 抗原表位

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    C-Term

    原理

    Cytokeratin 14 Antibody

    纯化方法

    Protein G affinity chromatography

    免疫原

    A synthetic peptide of 15 amino acid from the C-terminus of the human protein was used as the immunogen for the Cytokeratin 14 antibody.

    亚型

    IgG3, kappa
  • 应用备注

    Optimal dilution of the Cytokeratin 14 antibody should be determined by the researcher.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    0.1 mg/mL with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store the Cytokeratin 14 antibody at 2-8oC (up to one month) or aliquot and store at -20oC (longer term).
  • 抗原

    KRT14 (Keratin 14 (KRT14))

    别名

    Cytokeratin 14

    背景

    Cytokeratin 14 (CK14) belongs to the type I (or A or acidic) subfamily of low molecular weight keratins and exists in combination with keratin 5 (type II or B or basic). CK14 is found in basal cells of squamous epithelia, some glandular epithelia, myoepithelium, and mesothelial cells. Anti-CK14 is useful in differentiating squamous cell carcinomas from poorly differentiated epithelial tumors. Anti-CK14 is one of the specific basal markers for distinguishing between basal and non-basal subtypes of breast carcinomas. Anti-CK14 is also a good marker for differentiation of intraductal from invasive salivary duct carcinoma by the positive staining of basal cells surrounding the in-situ neoplasm as well as for differentiation of benign prostate from prostate carcinoma. Furthermore, this antibody has been useful in separating oncocytic tumors of the kidney from its renal mimics, and in identifying metaplastic carcinomas of the breast.

    UniProt

    P02533
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