UNG 抗体 (AA 96-313)
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Quick Overview for UNG 抗体 (AA 96-313) (ABIN7877249)
抗原
See all UNG 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 96-313
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原理
- UNG Antibody / Uracil-DNA Glycosylase
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纯化方法
- Affinity purified
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免疫原
- Recombinant human protein (amino acids E96-L313) was used as the immunogen for the UNG antibody.
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亚型
- IgG
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应用备注
- Optimal dilution of the UNG antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the UNG antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- UNG (Uracil-DNA Glycosylase (UNG))
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别名
- UNG
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背景
- Uracil-DNA glycosylase, also known as UNG or UDG, is a human gene though orthologs exist ubiquitously among prokaryotes and eukaryotes and even in some DNA viruses. The first uracil DNA-glycosylase was isolated from Escherichia coli. This gene encodes one of several uracil-DNA glycosylases. One important function of uracil-DNA glycosylases is to prevent mutagenesis by eliminating uracil from DNA molecules by cleaving the N-glycosylic bond and initiating the base-excision repair (BER) pathway. Uracil bases occur from cytosine deamination or misincorporation of dUMP residues. Alternative promoter usage and splicing of this gene leads to two different isoforms: the mitochondrial UNG1 and the nuclear UNG2. The UNG2 term was used as a previous symbol for the CCNO gene, which has been confused with this gene, in the literature and some databases.
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UniProt
- P13051
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途径
- DNA Damage Repair, Production of Molecular Mediator of Immune Response
抗原
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