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Recombinant NKX3-1 抗体 (AA 92-224)

The 小鼠 单克隆 anti-NKX3-1 antibody is suitable to detect NKX3-1 in samples from 人. It has been validated for ELISA 和 IHC (p).
产品编号 ABIN7877157
发货至: 中国
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Quick Overview for Recombinant NKX3-1 抗体 (AA 92-224) (ABIN7877157)

抗原

See all NKX3-1 抗体
NKX3-1 (NK3 Homeobox 1 (NKX3-1))

抗体类型

Recombinant Antibody

适用

  • 121
  • 20
  • 7
  • 4
  • 4
  • 4
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1

宿主

  • 69
  • 62
小鼠

克隆类型

  • 78
  • 53
单克隆

标记

  • 69
  • 9
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
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  • 3
  • 3
  • 3
  • 3
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This NKX3-1 antibody is un-conjugated

应用范围

  • 64
  • 60
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  • 26
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  • 5
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  • 2
  • 2
  • 1
ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

质量等级

Carrier-free

克隆位点

RNKX3-1-6620
  • 抗原表位

    • 50
    • 8
    • 8
    • 7
    • 7
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
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    • 1
    • 1
    • 1
    AA 92-224

    原理

    NKX3.1 Antibody (azide and preservative free)

    纯化方法

    Protein A/G affinity

    免疫原

    A portion of amino acids 92-224 was used as the immunogen for the NKX3.1 antibody.

    亚型

    IgG1, kappa
  • 应用备注

    Optimal dilution of the NKX3.1 antibody should be determined by the researcher.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    1 mg/mL in 1X PBS, BSA free, sodium azide free

    储存液

    Azide free

    储存条件

    -20 °C

    储存方法

    Aliquot the NKX3.1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
  • 抗原

    NKX3-1 (NK3 Homeobox 1 (NKX3-1))

    别名

    NKX3.1

    背景

    NKX3.1 is a prostate specific gene encoding a transcription factor that plays an important role in normal prostate development and carcinogenesis. It is a prostatic tumor suppressor gene located on chromosome 8p21.2, which frequently undergoes a loss of heterozygosity. NKX3.1 expression is highly restricted in prostate epithelial cells and therefore can be used as a diagnostic biomarker for prostate cancer and other metastatic lesions of prostatic origin. Furthermore, NKX3.1 shows better sensitivity than Prostate Specific Antigen (PSA) for identifying metastatic prostatic adenocarcinoma. This suggests that immunohistochemical staining of NKX3.1, along with other prostate-restricted markers, may be valuable for the definitive determination of prostatic origin in poorly differentiated metastatic carcinomas.

    UniProt

    Q99801

    途径

    Intracellular Steroid Hormone Receptor Signaling Pathway, Positive Regulation of Endopeptidase Activity, Positive Regulation of Response to DNA Damage Stimulus
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