PPP1R13B 抗体 (AA 901-1090)
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Quick Overview for PPP1R13B 抗体 (AA 901-1090) (ABIN7877127)
抗原
See all PPP1R13B 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 901-1090
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原理
- ASPP1 Antibody / PPP1R13B
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纯化方法
- Antigen affinity purified
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免疫原
- An E.coli-derived human recombinant protein (F901-A1090) was used as the immunogen for the ASPP1 antibody.
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亚型
- IgG
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应用备注
- Optimal dilution of the ASPP1 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the ASPP1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- PPP1R13B (Protein Phosphatase 1, Regulatory Subunit 13B (PPP1R13B))
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别名
- ASPP1
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背景
- Apoptosis-stimulating of p53 protein 1 is a protein that in humans is encoded by the PPP1R13B gene. This gene encodes a member of the ASPP (apoptosis-stimulating protein of p53) family of p53 interacting proteins. The protein contains four ankyrin repeats and an SH3 domain involved in protein-protein interactions. ASPP proteins are required for the induction of apoptosis by p53-family proteins. They promote DNA binding and transactivation of p53-family proteins on the promoters of proapoptotic genes. Expression of this gene is regulated by the E2F transcription factor.
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UniProt
- Q96KQ4
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途径
- p53 Pathway
抗原
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