SOX10 抗体 (AA 90-179)
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北京 101111
Quick Overview for SOX10 抗体 (AA 90-179) (ABIN7877102)
抗原
See all SOX10 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 90-179
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原理
- SOX10 Antibody
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纯化方法
- Protein A/G affinity
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免疫原
- A portion of amino acids 90-179 was used as the immunogen for the SOX10 antibody.
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亚型
- IgG2b
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anti-SRY (Sex Determining Region Y)-Box 10 (SOX10) (AA 115-269) antibody
SOX10 适用: 人, 小鼠 WB, IHC 宿主: 小鼠 Monoclonal SOX10-991 unconjugated
anti-SRY (Sex Determining Region Y)-Box 10 (SOX10) (AA 231-259) antibodySOX10 适用: 人, 小鼠, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB21835 unconjugated
anti-SRY (Sex Determining Region Y)-Box 10 (SOX10) (Middle Region) antibodySOX10 适用: 人, 小鼠, 大鼠, Cow, 犬, 兔, 豚鼠, 马 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-SRY (Sex Determining Region Y)-Box 10 (SOX10) (AA 147-252) antibodySOX10 适用: 人 FACS, ELISA 宿主: 小鼠 Monoclonal 2E7B5 unconjugated
anti-SRY (Sex Determining Region Y)-Box 10 (SOX10) (AA 147-252) antibodySOX10 适用: 人 IHC, ELISA 宿主: 小鼠 Monoclonal 2E7E8 unconjugated
anti-SRY (Sex Determining Region Y)-Box 10 (SOX10) (AA 115-269) antibodySOX10 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal SOX10-992 unconjugated
anti-SRY (Sex Determining Region Y)-Box 10 (SOX10) (AA 115-269) antibodySOX10 适用: 人, 小鼠 WB, IHC 宿主: 小鼠 Monoclonal rSOX10-1074 unconjugated Recombinant Antibody
anti-SRY (Sex Determining Region Y)-Box 10 (SOX10) (AA 115-269) antibodySOX10 适用: 人, 小鼠 WB, IHC 宿主: 兔 Monoclonal SOX10-2311R unconjugated Recombinant Antibody
anti-SRY (Sex Determining Region Y)-Box 10 (SOX10) antibodySOX10 适用: 人 WB, IHC, IF, ELISA 宿主: 兔 Monoclonal 8E1 unconjugated Recombinant Antibody
anti-SRY (Sex Determining Region Y)-Box 10 (SOX10) (AA 200-300) antibodySOX10 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal dilution of the SOX10 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.2 mg/mL
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缓冲液
- 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot the SOX10 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- SOX10 (SRY (Sex Determining Region Y)-Box 10 (SOX10))
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别名
- SOX10
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背景
- This MAb is highly specific and does not cross-react with other members of the SOX-family. SOX genes comprise a family of genes that are related to the mammalian sex-determining gene SRY. These genes similarly contain sequences that encode for the HMG-box domain, which is responsible for the sequence-specific DNA-binding activity. SOX10 is a sensitive marker of melanoma, including conventional, spindled, and desmoplastic subtypes. Expressed by metastatic melanomas and nodal capsular nevus in sentinel lymph nodes, but not by other lymph node components such as dendritic cells, which usually express S100 protein. Often used melanoma markers, such as anti-HMB45 and anti-MelanA, are poorly expressed in desmoplastic melanomas while SOX10 is moderately-to-strongly expressed in desmoplastic melanomas.
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UniProt
- P56693
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途径
- Chromatin Binding
抗原
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