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GJB2 抗体 (AA 88-137)

This 兔 多克隆 antibody specifically detects GJB2 in WB 和 ELISA. It exhibits reactivity toward 人, 小鼠 和 大鼠.
产品编号 ABIN7877027
发货至: 中国
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Quick Overview for GJB2 抗体 (AA 88-137) (ABIN7877027)

抗原

See all GJB2 抗体
GJB2 (Gap Junction Protein, beta 2, 26kDa (GJB2))

适用

  • 50
  • 28
  • 25
  • 5
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
人, 小鼠, 大鼠

宿主

  • 50
  • 6
  • 1

克隆类型

  • 51
  • 6
多克隆

标记

  • 38
  • 3
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This GJB2 antibody is un-conjugated

应用范围

  • 39
  • 30
  • 22
  • 6
  • 5
  • 5
  • 4
  • 2
  • 2
  • 1
  • 1
Western Blotting (WB), ELISA
  • 抗原表位

    • 7
    • 6
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 88-137

    原理

    Connexin 26 Antibody / GJB2

    纯化方法

    Antigen affinity purified

    免疫原

    Recombinant human protein (amino acids A88-T137) was used as the immunogen for the Connexin 26 antibody.

    亚型

    IgG
  • 应用备注

    Optimal dilution of the Connexin 26 antibody should be determined by the researcher.

    限制

    仅限研究用
  • 状态

    Lyophilized

    缓冲液

    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

    储存条件

    4 °C,-20 °C

    储存方法

    After reconstitution, the Connexin 26 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
  • 抗原

    GJB2 (Gap Junction Protein, beta 2, 26kDa (GJB2))

    别名

    Connexin 26

    背景

    Connexin 26 (CX26), also known as GAP junction protein, beta2, GJB2. Gap junctions were first characterized by electron microscopy as regionally specialized structures on plasma membranes of contacting adherent cells. These structures were shown to consist of cell-to-cell channels. Proteins, called connexins, purified from fractions of enriched gap junctions from different tissues differ. The 3-prime untranslated region of the CX26 transcript contains a putative mRNA instability sequence. The deduced 226-amino acid protein has a calculated molecular mass of about 26 kD. CX26 shares 92.5 % identity with rat Cx26. connexin 26 (GJB2) is assigned to human chromosome 13q11-q12 .Connexin 26 regulates epidermal barrier and wound remodeling and promotes psoriasiform response. Connexin 26 gene (GJB2) mutation modulates the severity of hearing loss associated with the 1555A-G mitochondrial mutation.

    UniProt

    P29033

    途径

    Sensory Perception of Sound, Cell-Cell Junction Organization
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