WISP2 抗体 (AA 87-116)
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Quick Overview for WISP2 抗体 (AA 87-116) (ABIN7877011)
抗原
See all WISP2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 87-116
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原理
- WISP-2 Antibody / WNT1-inducible-signaling pathway protein 2 / CCN5
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免疫原
- A portion of amino acids 87-116 from the human protein was used as the immunogen for this WISP-2 antibody.
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亚型
- Ig Fraction
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应用备注
- Titration of the WISP-2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot the WISP-2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- WISP2 (WNT1 Inducible Signaling Pathway Protein 2 (WISP2))
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别名
- WISP-2
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背景
- CCN5, also known as WISP-2 (Wnt-1-induced secreted protein 2), is a member of the CCN family of proteins that are involved in cell growth, differentiation, and migration. It is known for its ability to modulate signaling pathways that regulate various cellular activities, making it a key player in maintaining homeostasis in tissues. One of the primary functions of CCN5 is its role in regulating the growth and development of tissues, particularly in the cardiovascular system. Studies have shown that CCN5 can protect against cardiac fibrosis and hypertrophy, making it a potential therapeutic target for heart-related diseases. Furthermore, CCN5 has been found to have anti-inflammatory properties, making it a promising candidate for the treatment of inflammatory conditions. Its ability to regulate immune responses and modulate cytokine production highlights its potential as a target for managing inflammatory disorders. CCN5 has also been implicated in the regulation of metabolic processes and energy homeostasis. Research has shown that CCN5 can influence lipid metabolism and insulin sensitivity, suggesting its potential use in combating metabolic disorders such as obesity and diabetes.
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UniProt
- O76076
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途径
- WNT signaling, Growth Factor Binding
抗原
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