Recombinant CTNND1 抗体 (AA 868-968)
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Quick Overview for Recombinant CTNND1 抗体 (AA 868-968) (ABIN7877009)
抗原
See all CTNND1 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 868-968
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原理
- Recombinant CTNND1 Antibody / p120 Catenin / Catenin delta 1
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纯化方法
- Protein A/G affinity
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免疫原
- A portion of amino acids 868-968 was used as the immunogen for the recombinant CTNND1 antibody.
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亚型
- IgG1, kappa
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anti-Catenin (Cadherin-Associated Protein), delta 1 (CTNND1) antibody
CTNND1 适用: 人 WB, IHC, IP 宿主: 兔 Monoclonal unconjugated
anti-Catenin (Cadherin-Associated Protein), delta 1 (CTNND1) (AA 573-832) antibodyCTNND1 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Catenin (Cadherin-Associated Protein), delta 1 (CTNND1) antibodyKD Validated CTNND1 适用: 人 WB, IF (p), FACS 宿主: 兔 Monoclonal 23GB3025 unconjugated Recombinant Antibody
anti-Catenin (Cadherin-Associated Protein), delta 1 (CTNND1) antibodyKD Validated CTNND1 适用: 人 WB, FACS 宿主: 小鼠 Monoclonal 24GB5775 unconjugated
anti-Catenin (Cadherin-Associated Protein), delta 1 (CTNND1) antibodyCTNND1 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Catenin (Cadherin-Associated Protein), delta 1 (CTNND1) (AA 64-930) antibodyCTNND1 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, FACS, ICC 宿主: 兔 Polyclonal unconjugated
anti-Catenin (Cadherin-Associated Protein), delta 1 (CTNND1) (AA 64-930) antibodyCTNND1 适用: 人, 小鼠, 大鼠 WB, IHC, IF, ICC 宿主: 小鼠 Monoclonal 8G7E4 unconjugated
anti-Catenin (Cadherin-Associated Protein), delta 1 (CTNND1) antibodyCTNND1 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Catenin (Cadherin-Associated Protein), delta 1 (CTNND1) (Tyr228) antibodyCTNND1 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Catenin (Cadherin-Associated Protein), delta 1 (CTNND1) (AA 482-605) antibodyCTNND1 适用: 人 IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal dilution of the recombinant CTNND1 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.2 mg/mL
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缓冲液
- 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot the recombinant CTNND1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- CTNND1 (Catenin (Cadherin-Associated Protein), delta 1 (CTNND1))
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别名
- CTNND1
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背景
- Alpha-catenin and beta-catenin bind to the intracellular domain of E-cadherin while p120 catenin binds E-cadherin at a juxta-membrane site. The complex stabilizes tight junctions. In the cell, p120 catenin localized to the E-cadherin/catenins cell adhesion complex, directly associates with cytoplasmic C-terminus of E-cadherin and may similarly interact with other cadherins. p120 is a proliferation-associated nucleolar protein found in most human malignant tumors, but not in resting normal cells. In colorectal cancer the altered localization of p120 catenin corresponds with loss of cytoplasmic localization of E-cadherin. Studies have shown accurate categorization of ductal vs. lobular neoplasia in the breast was achieved with p120 staining. p120 expression further clarifies the separation of low-grade ductal carcinoma in situ from lobular neoplasia. Studies also have shown that altered expression of p120 catenin antibody predicts poor outcome in invasive breast cancer.
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UniProt
- O60716
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途径
- EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Cell-Cell Junction Organization, CXCR4-mediated Signaling Events, Platelet-derived growth Factor Receptor Signaling
抗原
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