EIF5A 抗体 (AA 86-154)
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北京 101111
Quick Overview for EIF5A 抗体 (AA 86-154) (ABIN7876994)
抗原
See all EIF5A 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 86-154
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原理
- Eukaryotic translation initiation factor 5A-1 Antibody / EIF5A
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纯化方法
- Antigen affinity purified
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免疫原
- Recombinant human protein (amino acids R86-K154) was used as the immunogen for the EIF5A antibody.
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亚型
- IgG
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anti-Eukaryotic Translation Initiation Factor 5A (EIF5A) (AA 1-154) antibody
EIF5A 适用: 人 WB, IF, IHC 宿主: 兔 Polyclonal unconjugated
anti-Eukaryotic Translation Initiation Factor 5A (EIF5A) (AA 1-154) antibodyEIF5A 适用: 人 IHC, ELISA, FACS, ICC 宿主: 小鼠 Monoclonal 4E10G8 unconjugated
anti-Eukaryotic Translation Initiation Factor 5A (EIF5A) (Internal Region) antibodyVerified EIF5A 适用: 人 WB, IHC, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Eukaryotic Translation Initiation Factor 5A (EIF5A) (AA 1-154) antibodyEIF5A 适用: 人 WB, IF, ELISA 宿主: 小鼠 Monoclonal 8C1 unconjugated
anti-Eukaryotic Translation Initiation Factor 5A (EIF5A) antibodyEIF5A 适用: 人 WB, IF, IHC, ELISA, FACS 宿主: 兔 Monoclonal 5E1 unconjugated Recombinant Antibody
anti-Eukaryotic Translation Initiation Factor 5A (EIF5A) antibodyEIF5A 适用: 人, 小鼠 WB, IF, IHC 宿主: 兔 Polyclonal unconjugated
anti-Eukaryotic Translation Initiation Factor 5A (EIF5A) antibodyKD Validated EIF5A 适用: 人 WB, FACS 宿主: 兔 Monoclonal 25GB2900 unconjugated Recombinant Antibody
anti-Eukaryotic Translation Initiation Factor 5A (EIF5A) (AA 107-154) antibodyEIF5A 适用: 人, 小鼠, 大鼠 WB, IF, ELISA, FACS, ICC 宿主: 兔 Polyclonal unconjugated
anti-Eukaryotic Translation Initiation Factor 5A (EIF5A) (Internal Region) antibodyEIF5A 适用: 人, 小鼠, 大鼠 WB, IF, IHC, ELISA, ICC 宿主: 兔 Polyclonal unconjugated
anti-Eukaryotic Translation Initiation Factor 5A (EIF5A) (AA 2-154) antibodyEIF5A 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal dilution of the Eukaryotic translation initiation factor 5A-1 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the Eukaryotic translation initiation factor 5A-1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- EIF5A (Eukaryotic Translation Initiation Factor 5A (EIF5A))
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别名
- Eukaryotic translation initiation factor 5A-1
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背景
- Eukaryotic translation initiation factor 5A-1 is a protein that in humans is encoded by the EIF5A gene. Eukaryotic initiation factor 5A (eIF5A) is an mRNA-binding protein that is involved in translation elongation and plays an important role in promoting translation of polyproline motifs. The eIF5A (eIF5A1) and eIF5A2 genes encode the two vertebrate eIF5A isoforms. While eIF5A1 is expressed constitutively in all tissues, eIF5A2 is mainly expressed in gonads. eIF5A and eIF5A2 are the only identified proteins that contain the distinctive amino acid hypusine, which is generated posttranslationally from lysine through a highly conserved polyamine metabolism pathway. eIF5A function and hypusine modification are both essential for cell proliferation, as knock down of eIF5A expression or blocking eIF5A hypusine modification suppresses cancer cell proliferation. Interestingly, eIF5A is an identified component of a tumor suppressor network of the polyamine-hypusine axis. Co-suppression of both eIF5A and adenosylmethionine decarboxylase 1 (AMD1) promotes lymphomagenesis in mice, while heterozygous deletions of the corresponding AMD1 and eIF5A genes often occur together in human lymphomas.
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UniProt
- P63241
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途径
- Regulation of Muscle Cell Differentiation
抗原
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