ECSIT 抗体 (AA 83-339)
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Quick Overview for ECSIT 抗体 (AA 83-339) (ABIN7876939)
抗原
See all ECSIT 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 83-339
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原理
- ECSIT Antibody
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纯化方法
- Antigen affinity purified
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免疫原
- Recombinant human protein (amino acids E83-S339) was used as the immunogen for the ECSIT antibody.
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亚型
- IgG
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anti-ECSIT (ECSIT) (AA 185-431) antibody
ECSIT 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-ECSIT (ECSIT) (AA 83-339) antibodyECSIT 适用: 人 WB, ELISA, IHC, IF, FACS, ICC 宿主: 兔 Polyclonal unconjugated
anti-ECSIT (ECSIT) (Middle Region) antibodyECSIT 适用: 人, 小鼠, 大鼠, Cow, 犬 WB 宿主: 兔 Polyclonal unconjugated
anti-ECSIT (ECSIT) (AA 20-431) antibodyECSIT 适用: 人 ELISA, PLA 宿主: 小鼠 Monoclonal 1B8 unconjugated
anti-ECSIT (ECSIT) (AA 241-290) antibodyECSIT 适用: 人, 小鼠, 大鼠, Cow, 马, 兔, Bat, Hamster, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-ECSIT (ECSIT) (AA 51-100) antibodyECSIT 适用: 小鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-ECSIT (ECSIT) (C-Term) antibodyECSIT 适用: 人, 小鼠 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
anti-ECSIT (ECSIT) antibodyECSIT 适用: 人 WB, IF/ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal dilution of the ECSIT antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the ECSIT antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- ECSIT
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别名
- ECSIT
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背景
- Evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial (ECSIT), also known as SITPEC, is a protein that in humans is encoded by the ECSIT gene. Activation of NF-kB as a result of Toll-like receptor (TLR) and IL-1 receptor signaling is a major component of innate immune responses. Signals from these receptors are relayed by a number of adapter molecules such as TRIF, TIRAP, and MyD88 to kinases such as IRAK and other intermediates such as TNF receptor associated factor (TRAF)-6. ECSIT (evolutionarily conserved signaling intermediate in Toll pathways) was initially identified as a cytoplasmic protein interacting specifically with TNF receptor associated factor (TRAF)-6 in the TLR pathway. Recently however, ECSIT has also been shown to be required for bone morphogenetic protein (Bmp) signaling and mesoderm formation during mouse embryogenesis, indicating the possibility of cross-talk between the TLR/IL-B and Bmp signaling pathways.
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UniProt
- Q9BQ95
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途径
- TLR signaling, Toll-Like Receptors Cascades, SARS-CoV-2 Protein Interactome
抗原
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