Elastase 3B 抗体 (AA 82-238)
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Quick Overview for Elastase 3B 抗体 (AA 82-238) (ABIN7876917)
抗原
See all Elastase 3B (ELA3B) 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
克隆位点
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抗原表位
- AA 82-238
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原理
- CELA3B Antibody (azide and preservative free)
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纯化方法
- Protein G affinity chromatography
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免疫原
- A portion of amino acids 82-238 from the human protein was used as the immunogen for the CELA3B antibody.
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亚型
- IgG3, kappa
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应用备注
- Optimal dilution of the CELA3B antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- 1 mg/mL in 1X PBS, BSA free, sodium azide free
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储存液
- Azide free
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储存条件
- 4 °C,-20 °C
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储存方法
- Store the CELA3B antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
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- Elastase 3B (ELA3B) (Elastase 3B, Pancreatic (ELA3B))
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别名
- CELA3B
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背景
- This MAb recognizes a protein of ~30 kDa, identified as CELA3B (Chymotrypsin like elastase family member 3B). Elastases form a subfamily of serine proteases that hydrolyze many proteins in addition to elastin. Humans have six elastase genes which encode the structurally similar proteins elastase 1, 2, 2A, 2B, 3A, and 3B. Unlike other elastases, elastase 3B has little elastolytic activity. Like most of the human elastases, elastase 3B is secreted from the pancreas as a zymogen and, like other serine proteases such as trypsin, chymotrypsin and kallikrein, it has a digestive function in the intestine. Elastase 3B preferentially cleaves proteins after alanine residues. Elastase 3B may also function in the intestinal transport and metabolism of cholesterol. Both elastase 3A and elastase 3B have been referred to as protease E and as elastase 1, and excretion of this protein in fecal material is frequently used as a measure of pancreatic function in clinical assays.
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UniProt
- P08861
抗原
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