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CPS1 抗体 (AA 800-100)

The 小鼠 单克隆 anti-CPS1 antibody (Clone CPS1-9869) (ABIN7876864) specifically detects CPS1 in WB 和 IHC (p). The antibody is reactive with 人 samples.
产品编号 ABIN7876864
发货至: 中国
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Quick Overview for CPS1 抗体 (AA 800-100) (ABIN7876864)

抗原

See all CPS1 抗体
CPS1 (Carbamoyl-Phosphate Synthase 1, Mitochondrial (CPS1))

适用

  • 113
  • 54
  • 39
  • 8
  • 4
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1

宿主

  • 86
  • 42
小鼠

克隆类型

  • 81
  • 47
单克隆

标记

  • 73
  • 7
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This CPS1 antibody is un-conjugated

应用范围

  • 71
  • 59
  • 28
  • 21
  • 17
  • 15
  • 14
  • 14
  • 3
  • 3
  • 2
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

质量等级

Carrier-free

克隆位点

CPS1-9869
  • 抗原表位

    • 15
    • 8
    • 8
    • 7
    • 5
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 800-100

    原理

    CPSase I Antibody / Carbamoyl phosphate synthetase 1 / CPS1 (azide and preservative free)

    纯化方法

    Protein A/G affinity

    免疫原

    A portion of amino acids 800-100 from human CPS1 protein was used as the immunogen for the CPSase I antibody.

    亚型

    IgG, kappa
  • 应用备注

    Optimal dilution of the CPSase I antibody should be determined by the researcher.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    1 mg/mL in 1X PBS, BSA free, sodium azide free

    储存液

    Azide free

    储存条件

    -20 °C

    储存方法

    Aliquot the CPSase I antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
  • 抗原

    CPS1 (Carbamoyl-Phosphate Synthase 1, Mitochondrial (CPS1))

    别名

    CPSase I

    背景

    This MAb recognizes a protein of 165 kDa, identified as carbamoyl phosphate synthetase 1 (CPS1). This mitochondrial enzyme catalyzes synthesis of carbamoyl phosphate from ammonia and bicarbonate. This reaction is the first committed step of the urea cycle, which is important in the removal of excess urea from cells. Deficiency of CPS1 is an autosomal recessive disorder that causes hyperammonemia. CPS1 is a hepatocyte specific protein that localizes to the mitochondria of hepatocytes. It is a sensitive marker for distinguishing hepatocellular carcinomas (HCC) from other metastatic carcinomas as well as cholangio-carcinomas. HCC s occur primarily in the stomach, but they are also found in many other organs. CPS1 may also be a useful marker for intestinal metaplasia. Reportedly, strong expression of CPS1 correlates with smaller tumor size and longer patient survival. Occasionally, CPS1 is also found in gastric carcinomas as well as in a few other non-hepatic tumors.

    UniProt

    P31327

    途径

    Response to Growth Hormone Stimulus, Cellular Glucan Metabolic Process
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