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Renin 抗体 (AA 80-370)

The 兔 多克隆 anti-Renin antibody (ABIN7876861) specifically detects Renin in WB, ELISA 和 IHC (p). The antibody is reactive with 人, 大鼠 和 小鼠 samples.
产品编号 ABIN7876861
发货至: 中国
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Quick Overview for Renin 抗体 (AA 80-370) (ABIN7876861)

抗原

See all Renin (REN) 抗体
Renin (REN)

适用

  • 70
  • 50
  • 35
  • 17
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
人, 大鼠, 小鼠

宿主

  • 82
  • 21
  • 19
  • 2
  • 2

克隆类型

  • 91
  • 34
多克隆

标记

  • 58
  • 19
  • 12
  • 6
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This Renin antibody is un-conjugated

应用范围

  • 97
  • 46
  • 46
  • 17
  • 17
  • 15
  • 13
  • 13
  • 11
  • 6
  • 5
  • 5
  • 3
  • 2
  • 2
  • 1
Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

    • 15
    • 6
    • 6
    • 6
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 80-370

    原理

    Renin Antibody / REN

    纯化方法

    Antigen affinity purified

    免疫原

    E. coli-derived recombinant human protein (amino acids N80-D370) was used as the immunogen for the Renin antibody.

    亚型

    IgG
  • 应用备注

    Optimal dilution of the Renin antibody should be determined by the researcher.

    限制

    仅限研究用
  • 状态

    Lyophilized

    缓冲液

    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

    储存条件

    4 °C,-20 °C

    储存方法

    After reconstitution, the Renin antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
  • 抗原

    Renin (REN)

    别名

    Renin

    背景

    This gene encodes renin, an aspartic protease that is secreted by the kidneys. Renin is a part of the renin-angiotensin-aldosterone system involved in regulation of blood pressure, and electrolyte balance. This enzyme catalyzes the first step in the activation pathway of angiotensinogen by cleaving angiotensinogen to form angiotensin I, which is then converted to angiotensin II by angiotensin I converting enzyme. This cascade can result in aldosterone release, narrowing of blood vessels, and increase in blood pressure as angiotension II is a vasoconstrictive peptide. Transcript variants that encode different protein isoforms and that arise from alternative splicing and the use of alternative promoters have been described, but their full-length nature has not been determined. Mutations in this gene have been shown to cause hyperuricemic nephropathy familial juvenile 2, familial hyperproreninemia, and renal tubular dysgenesis.

    UniProt

    P00797

    途径

    ACE Inhibitor Pathway, Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones, Feeding Behaviour
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