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SAV1 抗体 (AA 8-320)

The 兔 多克隆 anti-SAV1 antibody is suitable to detect SAV1 in samples from 人. It has been validated for WB, ELISA, IHC (p) 和 FACS.
产品编号 ABIN7876818
发货至: 中国
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Room 801-803
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for SAV1 抗体 (AA 8-320) (ABIN7876818)

抗原

See all SAV1 抗体
SAV1 (Salvador Homolog 1 (SAV1))

适用

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宿主

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克隆类型

  • 24
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多克隆

标记

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This SAV1 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)
  • 抗原表位

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    AA 8-320

    原理

    SAV1 Antibody / Protein salvador homolog 1 / WW45

    纯化方法

    Antigen affinity purified

    免疫原

    E. coli-derived recombinant human protein (amino acids K8-H320) was used as the immunogen for the SAV1 antibody.

    亚型

    IgG
  • 应用备注

    Optimal dilution of the SAV1 antibody should be determined by the researcher.

    限制

    仅限研究用
  • 状态

    Lyophilized

    缓冲液

    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

    储存条件

    4 °C,-20 °C

    储存方法

    After reconstitution, the SAV1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
  • 抗原

    SAV1 (Salvador Homolog 1 (SAV1))

    别名

    SAV1

    背景

    Protein salvador homolog 1 is a protein that in humans is encoded by the SAV1 gene. WW domain-containing proteins are found in all eukaryotes and play an important role in the regulation of a wide variety of cellular functions such as protein degradation, transcription, and RNA splicing. This gene encodes a protein with two WW domains, a SARAH domain, and a coiled-coil region and is ubiquitously expressed in adult tissues. This protein binds to MST1 (mammalian sterile 20-like kinase 1) and promotes MST1-induced apoptosis. It has also been shown to bind to HAX1 (hematopoietic cell-specific protein 1 (HS1)-associated protein X-1) and to attenuate the anti-apoptotic effects of HAX1. Studies in human and mouse suggest this gene acts as a tumor suppressor.

    UniProt

    Q9H4B6

    途径

    Stem Cell Maintenance
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