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IL12RB2 抗体 (AA 756-783)

This 兔 多克隆 antibody specifically detects IL12RB2 in WB, FACS 和 IHC (p). It exhibits reactivity toward 人.
产品编号 ABIN7876736
发货至: 中国
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Quick Overview for IL12RB2 抗体 (AA 756-783) (ABIN7876736)

抗原

See all IL12RB2 抗体
IL12RB2 (Interleukin 12 Receptor, beta 2 (IL12RB2))

适用

  • 50
  • 8

宿主

  • 42
  • 11
  • 1

克隆类型

  • 45
  • 9
多克隆

标记

  • 30
  • 5
  • 5
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This IL12RB2 antibody is un-conjugated

应用范围

  • 36
  • 20
  • 17
  • 16
  • 6
  • 5
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

    • 10
    • 6
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 756-783

    原理

    IL12RB2 Antibody

    纯化方法

    Antigen affinity purified

    免疫原

    A portion of amino acids 756-783 from the human protein was used as the immunogen for the IL12RB2 antibody.

    亚型

    Ig Fraction
  • 应用备注

    The stated application concentrations are suggested starting points. Titration of the IL12RB2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    In 1X PBS, pH 7.4, with 0.09 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Aliquot the IL12RB2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
  • 抗原

    IL12RB2 (Interleukin 12 Receptor, beta 2 (IL12RB2))

    别名

    IL12RB2

    背景

    The protein encoded by this gene is a type I transmembrane protein identified as a subunit of the interleukin 12 receptor complex. The coexpression of this and IL12RB1 proteins was shown to lead to the formation of high-affinity IL12 binding sites and reconstitution of IL12 dependent signaling. The expression of this gene is up-regulated by interferon gamma in Th1 cells, and plays a role in Th1 cell differentiation. The up-regulation of this gene is found to be associated with a number of infectious diseases, such as Crohn's disease and leprosy, which is thought to contribute to the inflammatory response and host defense.

    UniProt

    Q99665

    途径

    JAK/STAT Signaling
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