SYCP3 抗体 (AA 75-236)
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Quick Overview for SYCP3 抗体 (AA 75-236) (ABIN7876729)
抗原
See all SYCP3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 75-236
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原理
- Synaptonemal Complex Protein 3 Antibody / SYCP3
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纯化方法
- Antigen affinity purified
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免疫原
- Recombinant human protein (amino acids E75-F236) was used as the immunogen for the Synaptonemal Complex Protein 3 antibody.
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亚型
- IgG
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应用备注
- Optimal dilution of the Synaptonemal Complex Protein 3 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the Synaptonemal Complex Protein 3 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- SYCP3 (Synaptonemal Complex Protein 3 (SYCP3))
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别名
- Synaptonemal Complex Protein 3
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背景
- SYCP3, also known as COR1 or SCP3, is a protein that in humans is encoded by the SYCP3 gene. It is mapped to 12q23.2. This gene encodes an essential structural component of the synaptonemal complex. This complex is involved in synapsis, recombination and segregation of meiotic chromosomes. Mutations in this gene are associated with azoospermia in males and susceptibility to pregnancy loss in females. Alternate splicing results in multiple transcript variants that encode the same protein. SYCP3 has an essential meiotic function in human spermatogenesis that is compromised by the mutant protein by dominant-negative interference. SYCP3 is linked to inherited aneuploidy in female germ cells and provides a model system for studying age-dependent degeneration in oocytes.
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UniProt
- Q8IZU3
抗原
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